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Record W4404552450 · doi:10.1016/j.ttbdis.2024.102413

The distribution of Babesia odocoilei in Ixodes species ticks in Canada: Implications for one health surveillance

2024· article· en· W4404552450 on OpenAlexaffabout
Camille Guillot, Jérôme Pelletier, Cécile Aenishaenslin, Heather Coatsworth, Antonia Dibernardo, Jules K. Koffi, Manisha A. Kulkarni, Jean-Philippe Rocheleau, Christy Wilson, Curtis Russell, Mark P. Nelder, Jacqueline Badcock, Justin Carr, Sylvia Checkley, Katie M. Clow, Stephanie J. Cooper, Susan C. Cork, Ariane Dumas, Shaun J. Dergousoff, Nicoletta Faraone, Erin Fraser, Scott Graham-Derham, Alejandra Irace‐Cima, Stefan Iwasawa, Emily Jenkins, Patrick A. Leighton, Roman McKay, Muhammad Morshed, Roxane Pelletier, Marion Ripoche, Kateryn Rochon, Karine Thivierge, Maarten J. Voordouw, Nicholas H. Ogden, Catherine Bouchard

Bibliographic record

VenueTicks and Tick-borne Diseases · 2024
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsSte. Anne's HospitalUniversity of ManitobaInstitut National de Santé Publique du QuébecUniversity of British ColumbiaGovernment of ManitobaBC Centre for Disease ControlPublic Health Agency of CanadaUniversity of OttawaSimon Fraser UniversityUniversity of CalgaryAgriculture and Agri-Food CanadaUniversity of GuelphGovernment of New BrunswickCegep de Saint HyacinthePublic Health OntarioAcadia UniversityUniversity of SaskatchewanUniversité de Montréal
Fundersnot available
KeywordsIxodesBabesiaBiologyTick-borne diseaseVirologyGeographyTickZoology

Abstract

fetched live from OpenAlex

Ixodes scapularis and Ixodes pacificus are vectors of a range of pathogens of public health significance in North America. These ticks transmit pathogens to and from wild animal reservoir host species, but also bite humans and expose them to the pathogens. We describe the geographical and temporal distribution of the pathogen Babesia odocoilei, the causative agent of cervid babesiosis. Ixodes spp. ticks collected through active and passive surveillance were submitted to the National Microbiology Laboratory of the Public Health Agency of Canada for analysis of the presence of B. odocoilei from 2018 to 2021. Generalized linear models were constructed to evaluate the temporal change of B. odocoilei prevalence across Canada. Babesia odocoilei-positive I. scapularis are widespread across south-central and eastern regions of Canada, with an overall prevalence of 12.0 % in both nymphs (CI 95 % : 11.4-12.6) and adults (CI 95 % : 11.9-12.1) collected in passive surveillance and 13.2 % (CI 95 % : 12.9-13.5) and 10.0 % (CI 95 % : 9.8-10.2) in nymphs and adult, respectively, collected in active surveillance. A single I. pacificus tick tested positive in active surveillance out of 29 ticks collected in British Columbia, while no B odocoilei-positive I. scapularis were found in passive surveillance among the 11 adult ticks tested. Although B. odocoilei infection prevalence of adult I. scapularis was significantly higher in 2019 (14.1 %) than in 2018 (7.4 %), it remained stable from 2019 to 2021, suggesting that this pathogen may already be well established in endemic tick populations. The results provided in this article represent, to date, the most comprehensive picture of B. odocoilei distribution and prevalence in ticks in Canada and highlight the interest of maintaining One Health surveillance approaches to give added insight into disease transmission cycles for less well-characterized microorganisms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.389
Threshold uncertainty score0.834

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.250
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes2
Has abstractyes

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