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Canadian cannabis researcher perspectives on the conduct and sponsorship of scientific research by the for-profit cannabis industry

2024· article· en· W4404641879 on OpenAlexaffabout
Daniel Z. Buchman, Brooke Magel, Rowen Shier, Titilayo Esther Davies, Abhimanyu Sud, Shreya Mahajan, Roberta K. Timothy, Sophie Soklaridis, Quinn Grundy

Bibliographic record

VenueSocial Science & Medicine · 2024
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmaceutical industry and healthcare
Canadian institutionsPublic Health OntarioTrillium Health CentreCentre for Addiction and Mental HealthHumber River Regional HospitalUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsCannabisProfit (economics)For profitBusinessMarketingPublic relationsPolitical sciencePsychologyEconomicsPsychiatryFinance

Abstract

fetched live from OpenAlex

There has been considerable financial investment by the for-profit cannabis industry to conduct research on cannabis in Canada. Similar to peer industry counterparts such as the pharmaceutical, alcohol, tobacco, and food industries, there is evidence that for-profit cannabis companies are financially sponsoring research programs and researchers as well as non-financially, such as donating products. However, a large body of research has established that researchers' financial relationships with industries may influence research agendas, outcomes, lead to conflicts of interest, and bias the evidence base. Within a complex, emerging context of legalization, there is limited information on how cannabis researchers negotiate their relationships with the for-profit cannabis industry in Canada. Following a qualitative phenomenological methodology informed by moral experience for bioethics research, we conducted 38 semi-structured interviews with academic researchers, peer researchers, and clinicians with relevant perspectives about Canadian cannabis companies' research activities. We used a codebook approach to thematic analysis which generated three central themes: Navigating Systemic Barriers to Conduct Research; Impressions and Influences; and Guiding Principles for an Ethical Research Process. Our findings suggest that Canadian cannabis researchers tend to be morally ambivalent about cannabis industry sponsorship of research: they are motivated to conduct high quality research and generate evidence for population health benefit, yet they have concerns over the potential for research agenda bias created by these relationships which could be harmful to population health. Participants spoke how they relied heavily on personal values and individual strategies (transparency, value alignment, arms-length association, independence) to determine how they manage cannabis industry relationships. Our findings highlight how the issue of industry-academic relationships is a structural problem, thus individual-level solutions without attention to the relationship itself will only deepen ethical worries about industry-sponsored research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.057
metaresearch head score (Gemma)0.080
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Incentives · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.943
Threshold uncertainty score0.859

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0570.080
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.006
Science and technology studies0.0600.048
Scholarly communication0.0180.004
Open science0.0040.013
Research integrity0.0060.008
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.669
GPT teacher head0.635
Teacher spread0.034 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designQualitative
DomainIncentives
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes2
Has abstractyes

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