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Record W4404707478

[Comparative Profiles Of Breast Cancers According To Tumor Type At The Gabriel Touré University Hospital, Bamako - Mali, Between 2018 And 2022].

2024· article· en· W4404707478 on OpenAlexaff
Ibrahima Tegueté, A Sissoko, F M Sidibé, Fode Tounkara, D. Kassé, S Doumbia, F. Sidibé, Niani Mounkoro

Bibliographic record

VenuePubMed · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBreast Cancer Treatment Studies
Canadian institutionsUniversité Laval
Fundersnot available
KeywordsBreast tumorUniversity hospitalMedicineDemographyOncologyInternal medicineBreast cancerCancerSociology
DOInot available

Abstract

fetched live from OpenAlex

BACKGROUND: Few studies have been conducted on breast cancer despite its high burden in our context. Therefore, this study aimed to: (1) specify the sociodemographic and clinical characteristics of breast cancer; and (2) determine the factors associated with breast cancer survival at Gabriel Touré University Hospital (CHU). METHODS: , December 2022. Histologically confirmed cases of breast cancer were included and divided into three anatomoclinical groups (non-T4 tumor [NT4], locally advanced cancer [LAC] and inflammatory breast cancer [IBC]). We used Pearson's Chi-square or Fisher's Exact tests to compare proportions. The frequency distributions using density plots were constructed for the three breast types. They were compared using the Kruskal Wallis statistic. Kaplan-Meier curves were estimated for the survival analysis and Cox regression was used to identify factors associated with breast cancer survival. Adjusted hazard ratios (AHRs) and their 95% confidence intervals (95% CIs) were computed. RESULTS: A total of 255 cases of breast cancer were included in this study. The mean age was 46.9 years old. Whatever the anatomoclinical type, the density plot curve peaked before the age 40. NT4 and LAC were more frequently observed on the right breast, while IBC occurred on the left breast (p < 0.001). Comorbidity rates were comparable between the three groups. The median survival time was 9 months, and the overall 5-year survival rate was < 40%. Infertility history and IBC had a significant influence on survival, with AHRs of 1,63 [1,01 - 2,63] and 1,52 [1,04 - 2,22] respectively. CONCLUSION: Breast cancer at Gabriel Touré University Hospital is characterized by an early onset and a poor prognosis, suggesting that particular emphasis should be placed on early diagnosis and the quality of management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.034

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.234
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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