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Record W4404734802 · doi:10.1016/j.bionps.2024.100113

Subjective experience, psychosocial functioning and different psychomotor clusters in catatonia: How are they connected?

2024· article· en· W4404734802 on OpenAlexaff
Geva A. Brandt, Stefan Fritze, Dilsa Cemre Akkoc Altinok, Sebastian Volkmer, Jacqueline Kukovic, Jonas Daub, Katharina M. Kubera, Georg Northoff, Andreas Meyer‐Lindenberg, Dušan Hirjak

Bibliographic record

VenueBiomarkers in Neuropsychiatry · 2024
Typearticle
Languageen
FieldMedicine
TopicElectroconvulsive Therapy Studies
Canadian institutionsRoyal Ottawa Mental Health CentreUniversity of Ottawa
FundersDeutsche Forschungsgemeinschaft
KeywordsPsychomotor learningPsychosocialCatatoniaPsychologyClinical psychologyDevelopmental psychologyPsychotherapistPsychiatryCognitionSchizophrenia (object-oriented programming)

Abstract

fetched live from OpenAlex

Catatonia involves decreased, increased, and abnormal psychomotor activity, but most previous studies mainly focused on motor signs, neglecting the patients' subjective experiences. This study aimed to characterize psychomotor activity levels as introduced in the ICD-11 and their relation to subjectivity and overall psychosocial functioning in catatonia. We examined 54 patients with catatonia and 90 patients with schizophrenia spectrum- or mood disorders according to ICD-11 using an extensive battery of psychomotor-related clinical rating scales and Northoff Scale for subjective experience in catatonia (NSSC). For catatonia patients partial correlation coefficients between ICD-11 psychomotor clusters and their surrogate parameters were calculated. Group differences were analyzed using MANCOVA and post-hoc ANOVA. Finally, linear discriminant analysis (LDA) was used to examine the classification value of the respective rating scales and different surrogate parameters of ICD-11-related psychomotor activity. In catatonia patients decreased psychomotor activity was associated with psychomotor retardation (p<.05)), while increased activity was positively correlated with impulsivity and negatively correlated with psychomotor retardation (both p-values<.01). Abnormal psychomotor activity was positively associated with stereotypies as well as mannerisms, affectation and posturing. Significant group differences were observed in subjective experience, social performance, trait anxiety, psychomotor slowing, processing speed, and cognitive functioning. LDA revealed that the respective psychomotor-related rating scales are capable of distinguishing between diagnostic groups, albeit with varying degrees of classification accuracy (61.8 %-87.5 %). We identified a relationship between varying levels of psychomotor activity, subjective experiences, and psychosocial functioning in catatonia as defined by the ICD-11. Future large-scale studies are needed to validate these findings and refine assessment tools, such as the NSSC, by integrating subjective experiences with objective rating scales. This approach could pave the way for more tailored treatment options that consider the unique subjective experiences of catatonia patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.272
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2024
Admission routes1
Has abstractyes

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