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Record W4404897561 · doi:10.1111/pbr.13245

Assessing Single‐Trait and Multitrait Genomic Prediction Model Abilities Including Significant GWAS Markers for Fusarium Head Blight Disease Resistance in Wheat (<scp><i>Triticum aestivum</i></scp>)

2024· article· en· W4404897561 on OpenAlexafffund
Vinay Kumar Reddy Nannuru, Jon Arne Dieseth, Curt A. McCartney, María Antonia Henríquez, Hermann Buerstmayr, Sebastian Michel, Laura Morales, Theodorus Meuwissen, José Crossa, Morten Lillemo

Bibliographic record

VenuePlant Breeding · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsAgriculture and Agri-Food CanadaUniversity of Manitoba
FundersHorizon 2020 Framework ProgrammeNorges Miljø- og Biovitenskapelige UniversitetNorges ForskningsrådGenome Canada
KeywordsBiologyFusariumQuantitative trait locusGenome-wide association studyTraitPlant disease resistanceResistance (ecology)GeneticsAgronomyGeneGenotypeSingle-nucleotide polymorphism

Abstract

fetched live from OpenAlex

ABSTRACT Disease resistance traits are complex and quantitative in nature. Breeders regularly evaluate multiple important traits across diverse environments to employ them in genomics‐assisted breeding. In this study, we evaluated the prospects of genomic prediction models by incorporating genome‐wide association study (GWAS) results into single‐trait and multitrait genomic prediction scenarios, using two distinct panels: the NMBU panel and the GRAMINOR panel. A standard genomic prediction model ( Base ) and the Base model with the addition of significant GWAS markers as fixed covariates (Base + GWAS) were tested on both panels. The predictive ability of models was measured in terms of prediction ability by using Pearson's correlation method. An improvement of 0.05% to as high as a two‐fold improvement was observed in both the panels for single‐trait and multitrait scenarios. In general, multitrait models outperformed single‐trait models regardless of whether the GWAS markers were included. This study further concludes that multitrait‐based genomic predictions are superior to single trait–based ones when the associated traits are used and are well correlated.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.869
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.264
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes2
Has abstractyes

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