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Record W4405119473 · doi:10.54254/2753-8818/2024.18010

Research on schizophrenia – based on dementia, working memory and episodic memory deficits

2024· article· en· W4405119473 on OpenAlex
Q. Zhang

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueTheoretical and Natural Science · 2024
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsMcGill University
Fundersnot available
KeywordsDementiaSchizophrenia (object-oriented programming)PsychologyWorking memoryEpisodic memoryPsychiatryPrefrontal cortexPopulationCognitionMedicineDisease

Abstract

fetched live from OpenAlex

Schizophrenia is associated with severe cognitive dysfunctions, including memory deficits that affect both working memory (WM) and episodic memory (EM). Memory deficits are also a typical symptom experienced by dementia patients that causes crucial functional problems in daily life. Meanwhile, past studies yielded evidence for the relationship between dementia and psychiatric disorders, indicating the emergence of psychotic symptoms during prodromal dementia. This article aims to investigate the relationship between schizophrenia and dementia plus the WM and EM deficits among schizophrenia patients. In the first part of this paper, the association between schizophrenia and dementia is examined based on a psychosocial study conducted among the Danish population, comparing the likelihood of developing dementia in patients with schizophrenia to that of individuals without schizophrenia. The review of previous research findings indicates a positive correlation between a diagnosis of schizophrenia and the later development of dementia. This phenomenon may be due to the reason that schizophrenia is positively associated with several established risk factors of dementia. Then, the topic of the potential deficits of WM and EM is discussed using self-ordered task results and neurobiological evidence. Studies have showed that schizophrenia is likely to lead significant WM and EM limitations that are closely related to prefrontal cortex impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.481
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.004
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.350
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it