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Record W4405240979 · doi:10.1542/hpeds.2024-007990

Factors Associated With Early Computed Tomography Imaging in Children Hospitalized With Severe Orbital Infections

2024· article· en· W4405240979 on OpenAlexafffund
Winnie Yu, Cornelia M. Borkhoff, Sanjay Mahant, Olivier Drouin, Catherine Pound, Julie Quet, Gita Wahi, Ann Bayliss, Gemma Vomiero, Jessica L. Foulds, Ronik Kanani, Mahmoud Sakran, Anupam Sehgal, Jessica Cichon, Eleanor Pullenayegum, Elysa Widjaja, Arun Reginald, Nikolaus E. Wolter, Patricia C. Parkin, Peter J. Gill

Bibliographic record

VenueHospital Pediatrics · 2024
Typearticle
Languageen
FieldMedicine
TopicSinusitis and nasal conditions
Canadian institutionsQueen's UniversityLakeridge HealthNorth York General HospitalUniversity of AlbertaStollery Children's HospitalAlberta Children's HospitalUniversity of CalgaryKingston Health Sciences CentreInstitute for Clinical Evaluative SciencesUniversity of OttawaTrillium Health CentreHospital for Sick ChildrenUniversité de MontréalMcMaster UniversityMcMaster Children's HospitalCentre Hospitalier Universitaire Sainte-JustineChildren's Hospital of Eastern OntarioPublic Health OntarioUniversity of Toronto
FundersInstitute of Human Development, Child and Youth HealthCanadian Institutes of Health ResearchHospital for Sick ChildrenPhysicians' Services Incorporated Foundation
KeywordsMedicineComputed tomographyPediatricsRadiology

Abstract

fetched live from OpenAlex

OBJECTIVE: We identified factors associated with computed tomographic (CT) imaging within 24 hours of emergency department (ED) presentation in hospitalized children with severe orbital infections. PATIENTS AND METHODS: A multicenter retrospective cohort study was conducted that included children aged 2 months to 18 years between 2009 and 2018 who were admitted to the hospital with severe orbital infections, including periorbital and orbital cellulitis. Multivariable modified Poisson regression was used to identify possible factors associated with receiving a CT scan within 24 hours of ED presentation. RESULTS: Of 1144 children, 494 (43.2%) received a CT scan within 24 hours of ED presentation. Factors associated with receiving a CT scan within 24 hours included sex (male; adjusted relative risk [aRR], 1.18; 95% CI, 1.04-1.33), hospitalized at a children's hospital (aRR, 1.80; 95% CI, 1.32-2.45), consulted by both ophthalmology and otolaryngology (aRR, 3.12; 95% CI, 2.35-4.13) or either ophthalmology (aRR, 2.19; 95% CI, 1.66-2.90) or otolaryngology (aRR, 2.66; 95% CI, 1.84-3.86), and had proptosis (aRR, 1.39; 95% CI, 1.24-1.57) or eye swollen shut (aRR, 1.27; 95% CI, 1.13-1.43) as clinical signs upon ED presentation. Children aged younger than 5 years were less likely to receive early CT imaging (aRR, 0.63; 95% CI, 0.53-0.74). There were no associations between time of ED triage, temperature greater than 38 °C, or inflammatory markers with early CT imaging. CONCLUSION: Although several patient and hospital factors associated with early CT imaging decisions in children with severe orbital infections are associated with more severe infections, newly identified risk factors, such as inflammatory markers, were not. These findings will help better the understanding of clinical management and indications for CT imaging.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.907

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.223
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes2
Has abstractyes

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