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Record W4405399147 · doi:10.1111/mcn.13768

Assessment of Women's Discretionary Salt Intake and Household Salt Utilization in Preparation for a Salt Fortification Trial in Oromia Region, Ethiopia

2024· article· en· W4405399147 on OpenAlexaff
Isaac Agbemafle, Meseret Woldeyohannes, Masresha Tessema, Mengistu Fereja, Charles D. Arnold, Biniyam Tesfaye Banjaw, Alemayhu Hussen, Tadesse Kebebe, Yvonne E Goh, Mandana Arabi, Homero Martı́nez, Christine M. McDonald, Kenneth H. Brown

Bibliographic record

VenueMaternal and Child Nutrition · 2024
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsNutrition International
FundersBill and Melinda Gates Foundation
KeywordsMedicineFortificationFolic acidPercentileEnvironmental healthFood fortificationFortified FoodFood scienceVitaminInternal medicine

Abstract

fetched live from OpenAlex

There is a high incidence of neural tube defects (NTDs) in Ethiopia and folate insufficiency, a primary risk factor for NTDs, is common among Ethiopian women of reproductive age (WRA). Folic acid fortification of salt has been proposed as a strategy to control these problems. In preparation for an intervention trial to assess the nutritional effects of folic acid-fortified salt, we measured discretionary salt intakes among nonpregnant WRA using observed weighed food records, and we assessed household salt disappearance rates. We estimated the distribution of usual discretionary salt intake by adjusting for intra-individual variability using the National Cancer Institute (NCI) method, and we simulated the potential effects of two levels of folic acid fortification (30 and 90 ppm folic acid) on folic acid intakes. Mean ± SD of usual discretionary salt intake was 6.8 ± 1.9 g/day. At the 95th percentile of usual discretionary salt intake, the higher fortification level would provide 918 µg folic acid/day, which is less than the tolerable upper intake level of 1000 µg/day. At the 5th percentile of usual discretionary salt intake, the lower fortification level would provide 124 µg folic acid/day, which should produce a statistically significant increase in red blood cell folate concentration. Estimated household salt utilization was 8.8 ± 6.1 g/person/day. These findings inform plans for a randomized, dose-response intervention trial of folic acid-fortified salt and a possible future national program to mandate folic acid fortification of refined, edible salt in Ethiopia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.511
Threshold uncertainty score0.322

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.344
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2024
Admission routes1
Has abstractyes

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