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Record W4405431754 · doi:10.17615/7qdx-re77

Hospital Readmissions Among Persons With Human Immunodeficiency Virus in the United States and Canada, 2005-2018: A Collaboration of Cohort Studies

2023· article· en· W4405431754 on OpenAlexfundaboutno aff
Thibaut Davy-Méndez, Sonia Napravnik, Brenna Hogan, Joseph J. Eron, Kelly A. Gebo, Keri N. Althoff, Richard D. Moore, Michael J. Silverberg, Michael A. Horberg, M. John Gill, Peter F. Rebeiro, Maile Karris, Marina B. Klein, Mari M. Kitahata, Heidi M. Crane, Ank E. Nijhawan, Kathleen A. McGinnis, Jennifer E. Thorne, Viviane D. Lima, Ronald J. Bosch, Jonathan Colasanti, Charles S. Rabkin, Raynell Lang, Stephen A. Berry

Bibliographic record

VenueCarolina Digital Repository (University of North Carolina at Chapel Hill) · 2023
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsnot available
FundersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institute of Child Health and Human DevelopmentNational Institute of Allergy and Infectious DiseasesNational Institute of Mental HealthNational Institute of Nursing ResearchNational Institute on Deafness and Other Communication DisordersNational Heart, Lung, and Blood InstituteHealth Resources and Services AdministrationCenters for Disease Control and PreventionNational Institutes of HealthMcGill University Health CentreMcGill UniversityNational Cancer InstituteKaiser PermanenteCase Western Reserve UniversityUniversity of North Carolina at Chapel HillAgency for Healthcare Research and QualityGovernment of AlbertaUniversity of Texas Southwestern Medical CenterUniversity of WashingtonJohns Hopkins UniversityCanadian Institutes of Health ResearchVanderbilt University
KeywordsHuman immunodeficiency virus (HIV)CohortFamily medicineMedicineCohort studyGerontologyVirologyInternal medicine

Abstract

fetched live from OpenAlex

Background. Hospital readmission trends for persons with human immunodeficiency virus (PWH) in North America in the context of policy changes, improved antiretroviral therapy (ART), and aging are not well-known. We examined readmissions during 2005–2018 among adult PWH in NA-ACCORD. Methods. Linear risk regression estimated calendar trends in 30-day readmissions, adjusted for demographics, CD4 count, AIDS history, virologic suppression (<400 copies/mL), and cohort. Results. We examined 20 189 hospitalizations among 8823 PWH (73% cisgender men, 38% White, 38% Black). PWH hospitalized in 2018 versus 2005 had higher median age (54 vs 44 years), CD4 count (469 vs 274 cells/μL), and virologic suppression (83% vs 49%). Unadjusted 30-day readmissions decreased from 20.1% (95% confidence interval [CI], 17.9%–22.3%) in 2005 to 16.3% (95% CI, 14.1%–18.5%) in 2018. Absolute annual trends were −0.34% (95% CI, −.48% to −.19%) in unadjusted and −0.19% (95% CI, −.35% to −.02%) in adjusted analyses. By index hospitalization reason, there were significant adjusted decreases only for cardiovascular and psychiatric hospitalizations. Readmission reason was most frequently in the same diagnostic category as the index hospitalization. Conclusions. Readmissions decreased over 2005–2018 but remained higher than the general population’s. Significant decreases after adjusting for CD4 count and virologic suppression suggest that factors alongside improved ART contributed to lower readmissions. Efforts are needed to further prevent readmissions in PWH

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.256
Threshold uncertainty score0.860

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.239
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

Explore more

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