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Record W4405466495 · doi:10.1093/ofid/ofae728

A Behavioral Analysis of Factors That Influence Antibiotic Prescribing in Hospitals: A Metasynthesis of Reviews

2024· review· en· W4405466495 on OpenAlexafffund
Gracia Mabaya, Jenna M. Evans, Christopher J. Longo, Andrew M. Morris

Bibliographic record

VenueOpen Forum Infectious Diseases · 2024
Typereview
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsSinai Health SystemCanadian Centre for Applied Research in Cancer ControlUniversity of TorontoHamilton Health SciencesUniversity Health NetworkMcMaster University Medical CentreMcMaster University
FundersMcMaster University
KeywordsMedicineMeta-analysisAntibioticsFamily medicineInternal medicineMicrobiology

Abstract

fetched live from OpenAlex

Antibiotic resistance is a global public health threat driven, in part, by antibiotic overprescription. Behavior change theories are increasingly used to try to modify prescriber behavior. A metasynthesis of 8 reviews was conducted to identify factors influencing antibiotic prescribing for adults in hospital settings and to analyze these factors using 4 behavior change frameworks. Forty-three factors were identified across 7 thematic categories and then mapped to the theoretical domains framework and capability-opportunity-motivation model of behavior. The behavior change wheel and behavior change techniques taxonomy were then used to identify appropriate interventions and their components. The domain "environmental context and resources" was coded the most often, followed by "social influences" and "beliefs about consequences," revealing that prominent sources of antibiotic prescribing behavior are "physical opportunity" and "social opportunity." Based on these results, suggested interventions include environmental prompts/cues, education on consequences of antibiotic overuse, social comparison and support, and incentives.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.542
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0050.002
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.352
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes2
Has abstractyes

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