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Record W4405511913 · doi:10.1038/s44172-024-00328-8

Implantable silicon neural probes with nanophotonic phased arrays for single-lobe beam steering

2024· article· en· W4405511913 on OpenAlexafffund
Fu‐Der Chen, A. Sharma, Tianyuan Xue, Youngho Jung, Alperen Gövdeli, Jason C. C. Mak, Homeira Moradi Chameh, Mandana Movahed, Michael G. K. Brunk, Xianshu Luo, Hongyao Chua, Patrick Lo, Taufik A. Valiante, Wesley D. Sacher, Joyce K. S. Poon

Bibliographic record

VenueCommunications Engineering · 2024
Typearticle
Languageen
FieldNeuroscience
TopicPhotoreceptor and optogenetics research
Canadian institutionsToronto Western HospitalUniversity Health NetworkOntario Brain InstituteCentre for Addiction and Mental HealthUniversity of Toronto
FundersFraunhofer-Institut für Zelltherapie und ImmunologieNatural Sciences and Engineering Research Council of CanadaMax-Planck-Gesellschaft
KeywordsPhased-array opticsOptogeneticsBeam steeringPhased arrayMaterials scienceNanophotonicsGratingOpticsBeam (structure)OptoelectronicsComputer sciencePhysicsTelecommunicationsNeuroscience

Abstract

fetched live from OpenAlex

In brain activity mapping with optogenetics, patterned illumination is crucial for targeted neural stimulation. However, due to optical scattering in brain tissue, light-emitting implants are needed to bring patterned illumination to deep brain regions. A promising solution is silicon neural probes with integrated nanophotonic circuits that form tailored beam patterns without lenses. Here we propose neural probes with grating-based light emitters that generate a single steerable beam. The light emitters, optimized for blue or amber light, combine end-fire optical phased arrays with slab gratings to suppress higher-order sidelobes. In vivo experiments in mice demonstrated that the optical phased array provided sufficient power for optogenetic stimulation. While beam steering performance in tissue reveals challenges, including beam broadening from scattering and the need for a wider steering range, this proof-of-concept demonstration illustrates the design principles for realizing compact optical phased arrays capable of continuous single-beam scanning, laying the groundwork for advancing optical phased arrays toward targeted optogenetic stimulation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.308
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2024
Admission routes2
Has abstractyes

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