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Record W4405623972 · doi:10.29173/hsi418

To Resist or Not to Resist? That is the Dangerous Situation: A Look at Antimicrobial Stewardship in Pediatric Care in North America

2021· article· en· W4405623972 on OpenAlexvenueno aff
Rana Khafagy

Bibliographic record

VenueHealth Science Inquiry · 2021
Typearticle
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsnot available
Fundersnot available
KeywordsStewardship (theology)Antimicrobial stewardshipAntibiotic resistanceIntensive care medicineMedicineAntibiotic StewardshipResistance (ecology)AntibioticsHealth careVariety (cybernetics)Risk analysis (engineering)Environmental healthPolitical scienceComputer science

Abstract

fetched live from OpenAlex

This article will explore the impact of antibiotic resistance on pediatric care in North America, specifically focusing on how it negatively affects patient health outcomes. The mitigation of this issue in everyday health practice will be outlined. Antibiotics are one of the most commonly prescribed medications in children, with a significant number of them being used inappropriately. Considering the growing global threat of antibiotic resistant superbugs, it is vital to develop strategies and programs for decreasing antibiotic misuse and combating antibiotic resistance. Antimicrobial stewardship is one such method of reducing antibiotic resistance and has already shown evidence of improving patient outcomes, such as decreasing risk of future invasive infections, decreasing hospitalization and decreasing mortality. With more awareness to this dangerous issue, we are beginning to see the development and implementation of a variety of practices aimed at using antibiotics judiciously in pediatric patients across North America. This article will address the severity of the issue of antibiotic resistance in pediatric care in North America and highlight how this can be managed using antimicrobial stewardship principles that are practical, evidence-based and easily implementable in healthcare practices. Although there is still much work to be done, small improvements in resistance rates show that we are moving in the right direction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.038
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0040.003
Scholarly communication0.0030.003
Open science0.0010.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.331
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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