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Record W4405860008 · doi:10.5376/cmb.2024.14.0022

Protein-Protein Interaction Networks in Rice under Drought Stress: Insights from Proteomics and Bioinformatics Analysis

2024· article· en· W4405860008 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueComputational Molecular Biology · 2024
Typearticle
Languageen
FieldChemistry
TopicAdvanced Proteomics Techniques and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsProteomicsDrought stressComputational biologyBioinformaticsProtein Interaction NetworksBiologyComputer scienceProtein–protein interactionGeneticsBotanyGene

Abstract

fetched live from OpenAlex

This review outlines the physiological and biochemical responses of plants to drought stress, explains the molecular mechanisms, and emphasizes the key role of proteomics in these responses. Drought stress causes dehydration and osmotic changes in plants, leading to cell membrane damage, accumulation of reactive oxygen species (ROS), and metabolic disorders. Plants respond to drought stress through a series of complex physiological and biochemical responses, including regulate of stomatal opening and closing, synthesis protective proteins and metabolites, activate antioxidant systems, and regulate gene expression. Through proteomic and bioinformatic analysis, we systematically synthesis findings that identified key response proteins in rice under drought stress, constructed and analyzed the PPI network, performed functional annotation and pathway enrichment analysis, and demonstrated specific PPI networks involving transcription factors and signaling proteins, interaction networks with osmoprotectants and stress-related proteins, and comparative analysis of PPI networks of different rice varieties under drought stress through case studies. By exploring the response mechanism of rice under drought stress, we propose to develop more effective drought resistance strategies to improve the stability and sustainability of rice production.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.430
Threshold uncertainty score0.639

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.283
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it