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Comparison of urethral-sparing versus non urethral-sparing techniques of robot-assisted simple prostatectomy: a systematic review and meta-analysis of sexual, functional, and surgical outcomes

2024· review· en· W4405939718 on OpenAlexaboutno aff
Noka Yogahutama, Raden Danarto

Bibliographic record

VenueInternational Journal of Research in Medical Sciences · 2024
Typereview
Languageen
FieldMedicine
TopicProstate Cancer Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineProstatectomyMeta-analysisCochrane LibraryUrologySurgeryInternal medicineProstate

Abstract

fetched live from OpenAlex

Simple prostatectomy (SP) with urethral preservation offers various benefits. Recent advancements in technology have made urethral-sparing robot-assisted simple prostatectomy (US-RASP) more feasible. This systematic review compares the efficacy of US-RASP to non-urethral-sparing robot-assisted simple prostatectomy (Non-US-RASP). A systematic literature search was conducted on PubMed, Scopus, ProQuest, Cochrane Library, and ScienceDirect, following PRISMA 2020 guidelines up to September 2024. Meta-analyses of sexual, functional, and surgical outcomes were performed using Review Manager version 5.4. The risk of bias was assessed with the Newcastle-Ottawa scale (NOS). Six observational studies involving 615 patients were included (332 US-RASP versus 283 non-US-RASP). US-RASP significantly improved sexual outcomes, with higher 6-month ejaculatory preservation (OR 31.77, 95% CI: 13.28 to 76.02, p<0.001) and a higher 12-month MSHQ-EjD SF score (MD 6.38, 95% CI: 5.90 to 6.85, p<0.001). Surgical outcomes favored US-RASP with shorter catheterization time (MD -2.67, 95% CI: -4.63 to -0.71, p=0.008) and reduced length of stay (MD -1.39, 95% CI: -2.51 to -0.28, p=0.01). However, US-RASP was associated with a higher 12-month PVR score (MD 14.00, 95% CI: 12.33 to 15.68, p<0.001). This meta-analysis suggests that US-RASP is an effective alternative to Non-US-RASP, demonstrating better sexual and surgical outcomes despite a higher PVR. However, these findings should be confirmed with a well-designed larger randomized trial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.019
Threshold uncertainty score0.043

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.019
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0190.034
Bibliometrics0.0050.006
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.491
GPT teacher head0.598
Teacher spread0.107 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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