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Record W4405949615 · doi:10.1371/journal.pone.0295462

HIV prevention and missed opportunities among people with recently acquired HIV infection: Α protocol for a systematic review

2024· review· en· W4405949615 on OpenAlexaff
Argiro Karakosta, Elisa Ruiz-Burga, Shema Tariq, Giota Touloumi, Emily Jay Nicholls, Nikos Pantazis, Inmaculada Jarrín, Marc van der Valk, Caroline Sabin, Cristina Mussini, Laurence Meyer, Alain Volny Anne, Christina Carlander, Sophie Grabar, Linda Wittkop, Bruno Spire, Jonh Gill, Kholoud Porter, Fiona Burns

Bibliographic record

VenuePLoS ONE · 2024
Typereview
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsAlberta Hip and Knee Clinic
FundersJanssen PharmaceuticalsCity, University of LondonNational and Kapodistrian University of AthensInstitut National de la Santé et de la Recherche MédicaleKarolinska InstitutetUniversità Degli Studi di Modena e Reggio EmilaUniversity College LondonUniversity of Salford ManchesterMerck Sharp and DohmeCentre Hospitalier Universitaire de BordeauxInstituto de Salud Carlos IIIViiV HealthcareUniversiteit van Amsterdam
KeywordsPsycINFOSystematic reviewMedicineMEDLINEPopulationProtocol (science)Human immunodeficiency virus (HIV)Intervention (counseling)Family medicineAlternative medicineEnvironmental healthNursingPathology

Abstract

fetched live from OpenAlex

BACKGROUND: Individuals who have recently acquired HIV represent a unique population because the time frame since HIV acquisition is relatively short and identification of missed HIV prevention opportunities is, therefore, closer to real time and less subject to recall bias. Identifying prevention measures used and missed opportunities for using them, can help stop further HIV transmission. OBJECTIVES: This systematic review aims to synthesise current global evidence on uptake of HIV prevention methods among people with recently acquired HIV from 2007, the year that the concept of ART as a prevention method was first introduced. METHODS AND ANALYSIS: MEDLINE/PubMed, EMBASE, PsycINFO, Cochrane and Web of Science databases, will be searched for articles published January 2007-December 2023. Eligible studies will be those that reported on HIV prevention methods among people with recently acquired HIV. Quality assessment of the studies selected will be undertaken, and reporting of the systematic review will be informed by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RESULTS: The systematic review is expected to provide comprehensive insights into the uptake, use and adherence to HIV prevention methods among individuals with recently acquired HIV. Analysis anticipates identifying gaps in prevention coverage, missed opportunities for intervention, and variations in access to and use of prevention strategies. Sociodemographic, personal, and behavioural factors influencing prevention uptake and adherence will also be synthesised. CONCLUSIONS: The findings will be of key relevance to researchers, healthcare providers including third sector organisations/ community groups and policymakers, as they will offer insight into better understanding of missed or failed HIV prevention efforts and will help ensure future efforts meet the needs of those in need of them.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.126
metaresearch head score (Gemma)0.142
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.126
Threshold uncertainty score0.665

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1260.142
Meta-epidemiology (narrow)0.0080.008
Meta-epidemiology (broad)0.0230.021
Bibliometrics0.0190.018
Science and technology studies0.0060.007
Scholarly communication0.0090.011
Open science0.0060.007
Research integrity0.0110.011
Insufficient payload (model declined to judge)0.0570.009

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.221
GPT teacher head0.407
Teacher spread0.186 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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