Antibiothérapie et antibioprophylaxie de l'endocardite infectieuse – Une prise de position SPILF-AEPEI sur les recommandations 2023 de l'ESC
Bibliographic record
Abstract
• L'AEPEI et la SPILF proposent des recommandations sur le traitement antibiotique curatif et préventif de l'EI sur la base des recommandations de l'ESC publiées en 2023. • L'antibioprophylaxie chez les patients à haut risque d'EI ne doit être prescrite qu'avant une situation bucco-dentaire à risque. • Dans l'EI streptococcique, le choix de la β-lactamine doit être basé sur la CMI. • Dans l'EI prothétique staphylococcique, le traitement est une bithérapie associant β-lactamine ou daptomycine à la gentamicine puis la rifampicine après stérilisation des hémocultures. • Le relai oral de l'antibiothérapie orale est possible chez certains patients bien sélectionnés atteints d'EI streptococcique. • AEPEI and SPILF provide a consensus statement on the antibiotic treatment and prophylaxis of IE based on the ESC guidelines published in 2023. • Antibiotic prophylaxis in patients at high risk of IE should be prescribed only before oro-dental situations at risk. • In streptococcal IE, the choice of β-lactam should be based on the MIC. • In staphylococcal prosthetic valve IE, two antibiotics should be used, β-lactam or daptomycin with gentamicin replaced by rifampicin after sterilization of blood cultures. • Switch to oral antibiotic therapy may be used in selected patients with streptococcal IE.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.003 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".