MétaCan
Menu
Back to cohort
Record W4406130087 · doi:10.3389/fsybi.2024.1513580

Reduction of antimicrobial resistance genes in wastewater through phytoremediation

2025· article· en· W4406130087 on OpenAlexafffund
Kenton McCorquodale‐Bauer, Daniel Flores Orozco, Richard Grosshans, Francis Zvomuya, Nazim Çiçek

Bibliographic record

VenueFrontiers in Synthetic Biology · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsInternational Institute for Sustainable DevelopmentUniversity of Manitoba
FundersMitacs
KeywordsPhytoremediationAntimicrobialWastewaterAntibiotic resistanceBiotechnologyGeneResistance (ecology)BiologyMicrobiologyEnvironmental scienceGeneticsAntibioticsAgronomyEnvironmental engineeringContaminationEcology

Abstract

fetched live from OpenAlex

Developing strategies for the prevention of antimicrobial resistance genes (ARG) in wastewater treatment facilities, such as municipal wastewater sewage lagoons, is important to prevent ARG introduction and proliferation to the environment. While previous studies have shown promising results in reducing ARGs through biological and phytoremediation systems like Constructed Wetlands, the underlying mechanisms and the impact of water chemistry on ARG reduction remain poorly understood. This study used metagenomics to investigate the effect of three different biological wastewater treatments on the microbial community and resistome. The results indicated that each biological treatment significantly reduced ARGs and metal resistance genes (MRGs). A network analysis identified eight bacterial genera strongly associated with resistance genes, six of which belonged to the phylum Pseudomonadota and two to Campylobacteria. Of the six genera in Pseudomonadota, four were facultative anaerobes. A strong correlation was observed between iron (Fe) concentration in water and total ARG abundance ( r = 0.95), as well as between total metal concentration (across eight measured metals) and ARGs ( r = 0.93). Additionally, there was a significant correlation between ARG abundance and Fe resistance ( r = 0.86). This implies that high Fe and metal concentrations may favor ARG-harboring facultative bacteria by providing an electron donor for anaerobic respiration. This study suggests that phytoextraction of metals, including Fe, may play a significant role in reducing ARG abundance in treated water columns. These findings offer valuable insights into how metal removal and phytoremediation can effectively reduce ARG levels in wastewater.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.217
Threshold uncertainty score0.321

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.260
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueFrontiers in Synthetic BiologySame topicPharmaceutical and Antibiotic Environmental ImpactsFrench-language works237,207