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Record W4406142201 · doi:10.1016/j.afres.2025.100701

Monitoring of milk rennet coagulation: Chemical and physical perspective using Raman spectroscopy

2025· article· en· W4406142201 on OpenAlexaff
Leonardo Sibono, Stefania Tronci, Martin A.B. Hedegaard, Massimiliano Errico, Massimiliano Grosso

Bibliographic record

VenueApplied Food Research · 2025
Typearticle
Languageen
FieldChemistry
TopicSpectroscopy and Chemometric Analyses
Canadian institutionsInnovation Cluster (Canada)
FundersSyddansk Universitet
KeywordsRennetCoagulationRaman spectroscopyPerspective (graphical)ChemistryFood scienceMedicineComputer scienceInternal medicinePhysicsArtificial intelligenceOptics

Abstract

fetched live from OpenAlex

• Raman spectroscopy and chemometrics are effective in monitoring milk renneting. • Raman signal baseline variation analysis allows the curd cutting time prediction. • Rheological cutting time was modelled through Raman PC scores inflection time. • An R 2 of 0.872 was obtained in cutting time prediction from Raman signal variation. • Baseline correction helps identifying significant components of milk coagulation. The present study applies Raman spectroscopy and chemometrics to monitor the milk renneting process. Raman sensor information (Laser 785 nm) was simultaneously retrieved with rheological measurements to predict the curd cutting time. Principal component analysis was conducted on Raman spectra to collect the relevant information on the coagulating process. Rheological cutting time was modelled using the time at the inflection point of first Principal Component scores, from which an R 2 of 0.901 was obtained for calibration purposes, while 0.872 resulted from a 6-fold cross-validation. For the first time, the response of the Raman sensor was also used to assess the dynamic evolution of signal intensity for every individual Raman shift in order to identify which chemical bonds and molecules are significantly involved in the renneting process. To this concern, the role of tryptophan, P O 4 3 − groups, aspartic acid and phenylalanine results to be important in projecting the original spectra in the principal component subspace. Raman signals can be employed to study the physical behavior of renneting milk and to analyze the changes in chemical bonds, depending on the data pretreatment method applied, specifically in baseline correction. The presented results demonstrate that Raman spectroscopy can be successfully implemented to provide quantitative and qualitative knowledge of the milk coagulation process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.070
GPT teacher head0.414
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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