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Record W4406164769 · doi:10.1371/journal.pgph.0004022

Examining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States

2025· article· en· W4406164769 on OpenAlexafffund
Anh Khoa Vo, James A. G. Crispo, Lisa J.W. Liu, Dylan Thibault, Allison W. Willis, Donald Griesdale, John L. K. Kramer, Jacquelyn J. Cragg

Bibliographic record

VenuePLOS Global Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicPain Management and Treatment
Canadian institutionsCentre for Advancing Health OutcomesVancouver Coastal Health Research InstituteVancouver Coastal HealthNOSM UniversityInternational Collaboration On Repair DiscoveriesUniversity of British Columbia
FundersCanada Excellence Research Chairs, Government of CanadaNational Institute on AgingMichael Smith Health Research BC
KeywordsMedicineEmergency departmentOdds ratioEthnic groupComplex regional pain syndromeCross-sectional studyOddsChronic painDemographyPhysical therapyLogistic regressionInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

Complex regional pain syndrome is a chronic pain disorder marked by symptoms such as swelling, impaired motor function, and sympathetic dysfunction. Our primary objective was to determine the total number of complex regional pain syndrome type 1 (CRPS-1) emergency department (ED) visits and hospitalizations by race/ethnicity, as well as to assess sex and age distributions by race/ethnicity. Secondary objectives were to examine whether race/ethnicity, as well as select characteristics, are associated with hospitalization and longer length of stay. We completed a cross-sectional study of adults (19+ years) using acute and inpatient care data from the 2020 Nationwide Emergency Department Sample and the National Inpatient Sample. The overall rate of CRPS-1 diagnosis among ED visits and hospitalizations was 0.02% and 0.04%, respectively. Most CRPS-1 care was provided to White (ED: 83.1%; inpatient: 82.8%) patients. Within race/ethnicity groups, CRPS-1 ED visits and hospitalizations generally increased with age. Secondary findings included: 1) ED visits by Black individuals (compared with White) were significantly negatively associated with immediate hospitalization (adjusted odds ratio (AOR) 0.74, 95% CI 0.55 to 0.99); 2) hospitalizations by Black patients (compared with White) were independently associated with increased length of stay (odds ratio (OR) 1.45, 95% CI 1.07 to 1.96), though the association diminished with adjustment; and 3) drug abuse was significantly associated with hospitalization (AOR 4.67, 95% CI 3.53 to 6.18) and longer length of stay (AOR 1.81, 95% CI 1.34 to 2.46). Race/ethnicity was minimally associated with studied CRPS-1 outcomes. Additional studies are required to determine the impact of race/ethnicity on seeking care for CRPS-1.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.040

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.114
GPT teacher head0.358
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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