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Record W4406200968 · doi:10.1002/alz.088902

A Clinical Decision‐Making Tool to Identify Red Flags for Remote Cognitive Assessment: An Expert Consensus Study from the Canadian Consortium on Neurodegeneration in Aging

2024· article· en· W4406200968 on OpenAlexaffabout
Nathan Friedman, Inbal Itzhak, Philippe Desmarais, John D. Fisk, Linda Lee, Alexandre Henri‐Bhargava, Jacqueline A. Pettersen, Paula McLaughlin, Zahinoor Ismail, Vladimir Khanassov, Morris Freedman, Howard Chertkow, Richard Camicioli, Megan E. O’Connell, Maiya R. Geddes

Bibliographic record

VenueAlzheimer s & Dementia · 2024
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsMontreal Neurological Institute and HospitalUniversity of AlbertaBaycrest HospitalDalhousie UniversityHotchkiss Brain InstituteQueen's UniversityJewish General HospitalUniversity of Northern British ColumbiaUniversity of British ColumbiaUniversity of CalgaryMcGill UniversityCentre Hospitalier de l’Université de MontréalUniversity of SaskatchewanUniversity of VictoriaUniversity of Toronto
Fundersnot available
KeywordsWorkgroupContext (archaeology)Multidisciplinary approachDelphi methodCognitive declineCognitionMedicinePsychologyDementiaComputer sciencePsychiatryArtificial intelligencePathology

Abstract

fetched live from OpenAlex

Abstract Background Remote diagnostic assessment of cognitively impaired individuals offers numerous potential benefits including increased access to care. However, remote cognitive and behavioral assessment also has limitations, and may not be appropriate for certain patients. Currently, evidence‐based guidance on virtual assessment readiness is lacking. Our goal was to develop a clinical decision‐making tool that outlines an approach to determining a patient’s suitability for undergoing remote cognitive and behavioral diagnostic assessment by identifying ‘red flags’ for remote assessment. To address this goal, a multidisciplinary workgroup was convened under the auspices of the Canadian Consortium on Neurodegeneration in Aging (CCNA). This workgroup was composed of experts in remote assessment and included behavioral neurologists, neuropsychiatrists, neuropsychologists, social workers, geriatricians, persons with lived experience and family medicine specialists. Methods The Delphi process is an iterative, systematic, group consensus method, used here to determine the features of the patient, caregiver, clinician and context/situation, or ‘red flags’, indicating that a remote cognitive diagnostic assessment should be avoided. The process consisted of anonymized data collection in three rounds among the multidisciplinary expert workgroup, culminating in two rounds of iterative scoring of potential red flags based on three quality indicators that assessed a potential red flag’s effectiveness, reproducibility, and efficiency. Red flags that received an overall mean score above the pre‐determined consensus threshold on the final round were included in the final clinical decision‐making tool. Result In the first round, 11 respondents, with an average of 12.4 years of clinical experience, generated 67 unique potential red flags. In the second and third rounds, 8 and 9 respondents, respectively, scored the flags on the three quality indicators. Applying consensus criteria yielded 14 red flags that achieved consensus. Conclusion To enhance the translation and implementation of these findings, we developed a clinical decision‐making tool and infographic describing the final set of red flags in collaboration with the CCNA knowledge translation team. This infographic is designed to help clinicians determine a patient’s readiness to undergo remote cognitive assessment. This study directly impacts the clinical care of cognitively impaired individuals by providing clinical decision‐making guidance on a patient’s suitability for remote neurobehavioral assessment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.284
metaresearch head score (Gemma)0.260
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.963
Threshold uncertainty score0.883

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2840.260
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0060.004
Science and technology studies0.0080.003
Scholarly communication0.0040.002
Open science0.0040.007
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.470
Teacher spread0.378 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes2
Has abstractyes

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