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Record W4406320645 · doi:10.34119/bjhrv8n1-115

O imunocomprometimento e a relação com o desenvolvimento da candidíase oral: uma revisão de literatura

2025· article· pt· W4406320645 on OpenAlexaff
Jéssica Mirella Sales Duarte Lima, Yaritsan Fabia da Silva, Fernanda Braga Peixoto

Bibliographic record

VenueBrazilian Journal of Health Review · 2025
Typearticle
Languagept
FieldMedicine
TopicHIV/AIDS oral health manifestations
Canadian institutionsDiscovery Air (Canada)
Fundersnot available
KeywordsMedicineHuman immunodeficiency virus (HIV)GynecologyImmunology

Abstract

fetched live from OpenAlex

Este estudo revisa as estratégias de diagnóstico e manejo terapêutico da candidíase oral em pacientes imunocomprometidos, com foco nos fatores predisponentes, como HIV, quimioterapia e diabetes mellitus. A candidíase oral é uma infecção fúngica frequentemente observada em indivíduos com sistemas imunológicos comprometidos, sendo Candida albicans a principal responsável pela infecção. Embora presente na microbiota oral de indivíduos saudáveis, a proliferação excessiva desse fungo ocorre em condições de desequilíbrio imunológico, resultando em infecção. O objetivo desta pesquisa é examinar as abordagens mais recentes para o diagnóstico e tratamento da candidíase oral em pacientes imunocomprometidos, explorando a relação entre a infecção e as complicações sistêmicas, como a candidemia. A metodologia consistiu em uma revisão de literatura descritiva, com análise de artigos publicados entre 2004 e 2024 nas bases PubMed, SciELO, LILACS e Google Scholar, incluindo estudos sobre prevalência, fatores de risco, diagnóstico e opções terapêuticas. Os resultados indicam que a candidíase oral é uma das infecções mais comuns entre pacientes imunossuprimidos, especialmente aqueles com HIV/AIDS. Os tratamentos mais frequentes envolvem antifúngicos tópicos como fluconazol e nistatina, embora o aumento da resistência antifúngica seja uma preocupação crescente. Alternativas terapêuticas, como fototerapia antimicrobiana, têm mostrado eficácia, mas necessitam de mais evidências. O diagnóstico precoce e o controle das condições predisponentes são cruciais para o manejo eficaz da infecção.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.014
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0080.010
Science and technology studies0.0010.003
Scholarly communication0.0070.005
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.423
Teacher spread0.374 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venueBrazilian Journal of Health ReviewSame topicHIV/AIDS oral health manifestationsFrench-language works237,207