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A Novel Standard or Evolution in Treatment? A Systematic Review with Insights from Single-Center Experience on Robot-Assisted Urachal Excision and Partial Cystectomy for Urachal Pathologies

2025· review· en· W4406409505 on OpenAlexaboutno aff
Rafał B. Drobot, Grzegorz Stawarz, Marcin Lipa, Artur A. Antoniewicz

Bibliographic record

VenuePreprints.org · 2025
Typereview
Languageen
FieldMedicine
TopicUrinary and Genital Oncology Studies
Canadian institutionsnot available
Fundersnot available
KeywordsCystectomySingle CenterMedicineSurgeryInternal medicine

Abstract

fetched live from OpenAlex

Background: Ura-chal pathologies, while rare, pose a malignant transformation risk. RAUEPC is a mini-mally invasive technique with potential benefits, yet evidence remains limited. Methods: A systematic review was conducted in PubMed, Scopus, the Cochrane Library, and Sci-enceDirect (last search: 1 November 2024). Inclusion criteria: studies on RAUEPC for ura-chal pathologies. Exclusion criteria: non-robotic approaches or incomplete data. Risk of bias was assessed using the Newcastle-Ottawa Scale for cohort studies and the JBI Critical Appraisal Checklist for case reports. Descriptive statistics summarized continuous data (means, medians, 95% CIs), and chi-square tests analyzed associations between categori-cal variables. Heterogeneity analysis was infeasible, necessitating narrative synthesis. In-stitutional data (3 cases, 2021–2024) were included for comparison. Results: Forty-four studies (n = 145) met inclusion criteria. Benign lesions constituted 66.2% (95% CI: 59.1–73.3%) and malignant lesions 33.8% (95% CI: 26.7–40.9%). Mean operative time was 177.8 min (95% CI: 96.8–300), blood loss 83.3 mL (95% CI: 50–171), and hospital stay 3.9 days (95% CI: 1–10.9). Complications occurred in 33.3%. Institutional results showed a mean operative time of 85.3 min, blood loss of 216.7 mL, and no recurrences at 10.7 months’ fol-low-up. Discussion: RAUEPC appears to be a feasible and safe approach, showing prom-ising short-term outcomes. Associations between symptoms and diagnostic methods sug-gest its utility. Limitations include small sample sizes and retrospective designs. Registra-tion: PROSPERO: CRD42024597785. Funding: No external funding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.026
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0040.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.238
GPT teacher head0.423
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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