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Record W4406426593 · doi:10.1136/bmjopen-2024-088822

Development of a core patient-reported outcome set for use in HIV care at the individual patient level in Montreal: protocol for a two-phased multimethod project

2025· article· en· W4406426593 on OpenAlexafffundabout
Kim Engler, David Lessard, Karine Lacombe, Romain Palich, Bertrand Lebouché

Bibliographic record

VenueBMJ Open · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicDelphi Technique in Research
Canadian institutionsMcGill UniversityCentre for Advancing Health OutcomesMcGill University Health Centre
FundersHIV/AIDS and STBBI Research InitiativeCanadian Institutes of Health ResearchMerck CanadaMcGill University Health CentreViiV HealthcareMcGill UniversityGilead Sciences
KeywordsMedicineProtocol (science)Human immunodeficiency virus (HIV)Family medicinePatient-reported outcomeCore (optical fiber)Public healthOutcome (game theory)Health services researchHealth carePatient careAlternative medicineNursingQuality of life (healthcare)Pathology

Abstract

fetched live from OpenAlex

INTRODUCTION: There is international interest in using patient-reported outcome measures in HIV care to improve the well-being of people with HIV, but the prioritisation of specific outcomes and measures remains unclear. This project's objective is to engage both people with HIV and healthcare, social and community service providers to develop a French and English-language core set of patient-reported outcomes and measures for use in HIV care at the patient level in Montreal (Canada). METHODS AND ANALYSIS: This multimethod project will follow guidance from the Core Outcome Measures in Effectiveness Trials Initiative and involve two phases. Phase 1 will see the selection of the core set of outcomes (ie, the health concepts to target) and include a rapid scoping review to inform a Delphi study with a panel of 50 people with HIV and providers in Montreal. It will end with a multidisciplinary consensus meeting to make final decisions on the outcomes. Phase 2 will be devoted to choosing the measures to assess the selected outcomes. It will include a systematic search for instruments, an appraisal of the quality and feasibility of the identified instruments and a consensus meeting for the final selection. ETHICS AND DISSEMINATION: Research ethics board (REB) approval was obtained on 9 December 2024, from the institutional REB of the Research Institute of the McGill University Health Centre (reference number: 2024-9695). Findings will primarily be disseminated to (1) healthcare and social service providers through academic rounds and a provincial continuing education programme for HIV clinicians; (2) to people with HIV through partner community organisations and (3) a range of stakeholders at local, national and international conferences and through peer-reviewed publications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.223
metaresearch head score (Gemma)0.145
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.988
Threshold uncertainty score0.958

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2230.145
Meta-epidemiology (narrow)0.0040.004
Meta-epidemiology (broad)0.0060.008
Bibliometrics0.0060.008
Science and technology studies0.0070.006
Scholarly communication0.0070.005
Open science0.0060.007
Research integrity0.0070.007
Insufficient payload (model declined to judge)0.0610.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.685
GPT teacher head0.626
Teacher spread0.059 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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