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Record W4406530494 · doi:10.3126/njn.v21i3.66522

Scope on triglyceride levels in elderly patients with dementia versus controls: a systematic review and meta-analysis

2024· review· en· W4406530494 on OpenAlexaboutno aff
Heba Ramadan

Bibliographic record

VenueNepal Journal of Neuroscience · 2024
Typereview
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsnot available
Fundersnot available
KeywordsDementiaMeta-analysisScope (computer science)MedicineSystematic reviewMEDLINEPsychologyGerontologyComputer scienceInternal medicineDiseaseChemistryBiochemistry

Abstract

fetched live from OpenAlex

Introduction: Triglyceride levels vary among elderly patients with dementia. In this study, triglyceride levels were examined to demonstrate whether they increase or decrease in elderly dementia patients and other elderly individuals, whether there is a difference between elderly individuals with different forms of dementia and controls, and whether that difference is considered significant. Methods and materials: This analysis was performed via searching in Scopus, Web of Science, and Pubmed. A PRISMA checklist was followed to conduct the systematic review. The quality assessment was assessed by the Newcastle-Ottawa for case-control studies. Meta-analysis was performed by SPSS, Version 28. Results: Twenty-five studies consisting of 18943 cases and 212144 controls were included in the final analysis. Eighteen studies showed that the triglyceride levels in both patients and controls did not exceed the normal range (1.7 mmol/L or 150 mg/dl). A meta-analysis was also performed for the seven studies that revealed that triglyceride levels exceeded the normal range and no significant difference was found between the cases and controls (p-value =0.18, 95% CI). Conclusion: Triglyceride levels may not be a serious factor that should be considered in dementia, which differs from other areas of medicine, such as cardiovascular diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.031
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.015
Threshold uncertainty score0.068

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.031
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0150.022
Bibliometrics0.0060.007
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.145
GPT teacher head0.386
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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