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Record W4406687176 · doi:10.1097/ijg.0000000000002538

Goniotomy for Childhood Glaucoma Secondary to Uveitis: Long-Term Outcomes

2025· article· en· W4406687176 on OpenAlexaff
Tiki Ewing, Nicolás Correa, Sharon Armarnik, Christopher J. Lyons

Bibliographic record

VenueJournal of Glaucoma · 2025
Typearticle
Languageen
FieldMedicine
TopicOcular Diseases and Behçet’s Syndrome
Canadian institutionsBC Children's Hospital
Fundersnot available
KeywordsMedicineIntraocular pressureUveitisGlaucomaContext (archaeology)OphthalmologyCongenital glaucomaGlaucoma surgeryVisual acuityRetrospective cohort studySurgery

Abstract

fetched live from OpenAlex

PRÉCIS: Goniotomy is effective in managing intraocular pressure in childhood glaucoma secondary to uveitis with a cumulative probability of success 0.94 after 1 year and 0.77 after 5 years. OBJECTIVE: To evaluate the long-term success of goniotomy for childhood glaucoma secondary to chronic uveitis. METHODS: Retrospective chart review of all children treated with goniotomy for this indication from 2001 to 2023. Postoperative success was defined as IOP ≥ 6 and ≤ 21 mmHg after 1 or 2 goniotomies, without the need for further surgical intervention or sight-threatening complication. RESULTS: Thirty-one eyes of 21 patients were included. The mean age at first goniotomy was 10.3 years (range 6.6-15.7 years) with uveitis diagnosed on average 4.7 years earlier. The mean preoperative IOP was 28.8 mmHg, on a median of 4 topical agents. Mean follow-up post-goniotomy was 6.8 years (Median 5.7 y) and average postoperative IOP at 1, 5, and 8 years postoperatively was 15.9, 15.2, and 15.6 mmHg, respectively. At the most recent follow-up, 24 eyes (77.4%) were a surgical success. Of these, 5 (21%) needed a second goniotomy to achieve this, and 5 (21%) needed anti-glaucoma drops to maintain IOP ≤21 mmHg (2 of these also had a second goniotomy). There were no major complications, including loss of inflammatory control. CONCLUSION: We confirm that this quick, safe, conjunctival-sparing primary approach is safe and effective in this context, and early success rates are usually maintained in the long term. If stable inflammatory control can be achieved preoperatively, we recommend it as first-line treatment for children with childhood glaucoma secondary to uveitis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.019
Threshold uncertainty score0.800

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.299
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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