MétaCan
Menu
Back to cohort
Record W4406716147 · doi:10.1016/s2352-4642(24)00330-4

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis

2025· review· en· W4406716147 on OpenAlexaff
Anthony J. Garcia‐Prats, Maria Garcia‐Cremades, Vivian Cox, Tamara Kredo, Rory Dunbar, H. Simon Schaaf, James A. Seddon, Jennifer Furin, Jay Achar, Kendra Radke, Tina Sachs, Amanzhan Abubakirov, Saman Ahmed, Onno W. Akkerman, Nadia Abdulkareem Al Ani, Farhana Amanullah, Nafees Ahmad, Laura Anderson, Meseret Asfaw, Funeka Bango, Torsten T. Bauer, Mercedes C. Becerra, Martin J. Boeree, Folke Brinkmann, Rosemary Brown, James C.M. Brust, Jonathon R. Campbell, Anna Cristina Calçada Carvalho, Isabel Carvalho, J. Peter Cegielski, Rosella Centis, Edward D. Chan, Sandeep Chauhan, Silvia S. Chiang, Pei‐Chun Chan, Lia D’Ambrosio, Margareth Pretti Dalcolmo, Narine Daneilyan, Gèrard de Vries, Heather R. Draper, Lee Fairlie, Joshua Francis, Molly F. Franke, Medea Gegia, Camilo Gomez Restrepo, A. Guenther, Tatyana Gureva, Brit Haecker, Elizabeth Harausz, Catherine Hewison, Robert M. Hicks, Helena Huerga, Jennifer Hughes, Petros Isaakidis, Mazhar Ali Khan, Tinatin Kotrikadze, Līga Kukša, Nathalie Lachenal, Christoph Lange, Leonid Lecca, Elisa López‐Varela, Sheila Cunha Lucena, Andrei Mariandyshev, Sanjay Mattoo, Ana Méndez‐Echevarría, Giovanni Battista Migliori, Carole D. Mitnick, Erika Mohr-Holland, Winston Mulanda, Totugul Murzabakova, Bakyt Myrzalieve, Norbert Ndjeka, Stefan Niemann, Iveta Ozere, Nesri Padayatchi, Malik Parmar, Nargiza Parpieva, Mohammad Manzur-ul-Alam, Natasha Rybak, Kuldeep Singh Sachdeva, Kelly Salmon, Dagmar Schaub, Ira Shah, Sarita Shah, Sangeeta Sharma, Tae Sun Shim, Sonya Shin, Animesh A. Sinha, Alena Skrahina, Hardik Solanki, Belén P. Solans, Antoni Soriano‐Arandes, Atyrkul Toktogonova, Tjip S. van der Werf, Gustavo E. Velásquez, Bhanu Williams, Jae‐Joon Yim, Anneke C. Hesseling

Bibliographic record

VenueThe Lancet Child & Adolescent Health · 2025
Typereview
Languageen
FieldMedicine
TopicTuberculosis Research and Epidemiology
Canadian institutionsMcGill UniversityMcGill University Health Centre
FundersNational Institute of Allergy and Infectious DiseasesWorld Health Organization
KeywordsMeta-analysisMedicineTuberculosisAssociation (psychology)RifampicinMEDLINEInternal medicinePsychologyBiologyPathologyPsychotherapist

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.015
Threshold uncertainty score0.044

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.023
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0150.040
Bibliometrics0.0030.005
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.159
GPT teacher head0.397
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2025
Admission routes1
Has abstractno

Explore more

Same venueThe Lancet Child & Adolescent HealthSame topicTuberculosis Research and EpidemiologyFrench-language works237,207