MétaCan
Menu
← Back to cohort
Record W4406722266 · doi:10.1101/2025.01.21.634094

Meta all the way down: An overview of neuroimaging meta-analyses

2025· preprint· en· W4406722266 on OpenAlexaff
Kendra Oudyk, Jérôme Dockès, Julio A. Peraza, James D. Kent, Mohammad Torabi, Michelle Wang, Brent McPherson, Niusha Mirhakimi, Alejandro de la Vega, Angela R. Laird, Jean‐Baptiste Poline

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
Fundersnot available
KeywordsNeuroimagingMeta-analysisPsychologyComputer scienceMedicineNeuroscienceInternal medicine

Abstract

fetched live from OpenAlex

Abstract Meta-analyses are invaluable tools for navigating the rapidly expanding scientific literature. Given their high value, ensuring the quality of meta-analyses is paramount. We conducted a multifaceted overview, examining each step in a manual neuroimaging meta-analysis on a large scale. We used four novel datasets comprising over 14,000 papers, including fMRI meta-analyses, fMRI studies, studies included in meta-analyses, and studies associated with image data on NeuroVault. Regarding successes, two-thirds of meta-analyses stated that they followed PRISMA guidelines, and 65% included a flowchart describing their inclusion process. We point out several areas for improvement. Pre-registration was fairly rare (20%), and only half listed their exact search strategy. There could be a location bias in which papers are included, and many did not include enough studies to be robust against publication bias (68% of meta analyses have less than 30 studies included). We also offer ideas for future directions. As image based meta-analysis is the gold standard, we have indicated which topics have the most image data available. The potential redundancy of topics can be visualized in our paper, and we recommend future meta-analyses be in conversation with past ones by citing and discussing previous similar work. By addressing these findings, the neuroimaging community can collectively improve the field of neuroimaging meta-analyses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.078
metaresearch head score (Gemma)0.228
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.922
Threshold uncertainty score0.412

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0780.228
Meta-epidemiology (narrow)0.0040.004
Meta-epidemiology (broad)0.0130.026
Bibliometrics0.0300.022
Science and technology studies0.0010.001
Scholarly communication0.0070.006
Open science0.0040.004
Research integrity0.0030.006
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.788
GPT teacher head0.501
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicMeta-analysis and systematic reviews→French-language works237,207→