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Record W4406774899 · doi:10.11124/jbies-24-00279

Conducting pairwise and network meta-analyses in updated and living systematic reviews: a scoping review protocol

2025· review· en· W4406774899 on OpenAlexafffund
M. Konstantinidis, Catherine Stratton, Sofia Tsokani, Julian Elliott, Mark Simmonds, Jessie McGowan, David Moher, Andrea C. Tricco, Areti-Angeliki Veroniki

Bibliographic record

VenueJBI Evidence Synthesis · 2025
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsOttawa HospitalUniversity of OttawaPublic Health OntarioUniversity of TorontoSt. Michael's Hospital
FundersCanadian Institutes of Health ResearchPierre Elliott Trudeau Foundation
KeywordsSystematic reviewPsycINFOMEDLINEComputer scienceMeta-analysisGrey literatureInformation retrievalProtocol (science)Data scienceCochrane LibraryPairwise comparisonMedicineArtificial intelligenceAlternative medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: The objective of this scoping review is to describe existing guidance documents or studies reporting on the conduct of meta-analyses in updated systematic reviews (USRs) or living systematic reviews (LSRs). INTRODUCTION: The rapid increase in the medical literature poses a substantial challenge in keeping systematic reviews up to date. In LSRs, a review is updated with a pre-specified frequency or when some other signalling criterion is triggered. While the LSR framework is well-established, there is uncertainty regarding the most appropriate methods for conducting repeated meta-analyses over time, which may result in sub-optimal decision-making. INCLUSION CRITERIA: Studies of any design (including commentaries, books, manuals) providing guidance on conducting meta-analysis in USRs or LSRs. METHODS: This review will use the JBI methodology for scoping reviews. We will search multiple medical bibliographic databases (Cochrane Library, Embase, ERIC, MEDLINE, JBI Evidence Synthesis , and PsycINFO), statistical and mathematics databases (COBRA, Current Index to Statistics, MathSciNet, Project Euclid Complete, and zbMATH), pre print archives (Arvix, BioRxiv, and MedRxiv), and unpublished (or gray) literature sources. Two reviewers will independently screen titles, abstracts, and full-text documents, and extract data. Characteristics of recommendations for meta-analysis in USRs and LSRs will be presented using descriptive statistics and categorized concepts. REVIEW REGISTRATION: Open Science Framework https://osf.io/9c27g.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.209
metaresearch head score (Gemma)0.236
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.791
Threshold uncertainty score0.976

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2090.236
Meta-epidemiology (narrow)0.0060.007
Meta-epidemiology (broad)0.0140.019
Bibliometrics0.0200.019
Science and technology studies0.0060.007
Scholarly communication0.0100.012
Open science0.0070.009
Research integrity0.0130.010
Insufficient payload (model declined to judge)0.0990.033

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.855
GPT teacher head0.621
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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