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Record W4406791623 · doi:10.1016/j.jointm.2024.12.006

Anemia as a potent marker of in-hospital mortality in patients admitted to the cardiac intensive care unit: Data from the Critical Care Cardiology Trials Network (CCCTN) Registry

2025· article· en· W4406791623 on OpenAlexaff
Christine Chow, Rasheed Durowoju, Carlos L. Alviar, Gregory W. Barsness, Howard A. Cooper, Lori B. Daniels, Xuan Ding, Shahab Ghafghazi, Umesh Gidwani, Michael Goldfarb, Dustin Hillerson, Jason N Katz, Paul Marano, Jeong‐Gun Park, Matthew Pierce, Scott W. Rose, Robert O. Roswell, Sean van Diepen, Anjali Wagle, Erin A. Bohula, David D. Berg, David A. Morrow, Younghoon Kwon

Bibliographic record

VenueJournal of Intensive Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicErythropoietin and Anemia Treatment
Canadian institutionsUniversity of AlbertaMcGill University
FundersNational Institutes of HealthAmerican Heart Association
KeywordsMedicineIntensive care unitInternal medicineIntensive care medicineCardiologyEmergency medicineAnemia

Abstract

fetched live from OpenAlex

Background: Anemia is common in critically ill patients and is associated with poor outcomes. We investigated the prevalence of anemia and its association with in-hospital outcomes among patients admitted to cardiac intensive care units (CICUs) and subgroups within this population. Methods: The Critical Care Cardiology Trials Network (CCCTN) is a multicenter network of tertiary CICUs in North America. CICU admissions with available baseline hemoglobin (Hgb) between 2017 and 2023 were included in this analysis. Patients were stratified by Hgb levels (Hgb <8 g/dL, 8 g/dL ≤ Hgb <10 g/dL, 10 g/dL ≤ Hgb <12 g/dL, 12 g/dL ≤ Hgb <14 g/dL, and ≥14 g/dL). The ≥14 g/dL group was used for reference. The association of Hgb level and in-hospital mortality was examined by multivariable logistic regression. Results: =7194). Conclusions: Anemia was present in nearly half of patients admitted to CICUs. Lower admission Hgb is independently associated with higher in-hospital mortality in a graded relationship among patients with cardiac critical illness.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.026

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.012
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.385
Teacher spread0.327 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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