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Record W4406868100 · doi:10.1089/wound.2024.0213

Treatment of Surgical Scars with Fractional Carbon Dioxide (CO <sub>2</sub> ) Laser: A Randomized Controlled Trial

2025· article· en· W4406868100 on OpenAlexaboutno aff
L.-F. Chen, Xu Han, Q. Wang, Peng Chen, Lin Wang, Xiao Qin

Bibliographic record

VenueAdvances in Wound Care · 2025
Typearticle
Languageen
FieldMedicine
TopicDermatologic Treatments and Research
Canadian institutionsnot available
Fundersnot available
KeywordsRandomized controlled trialCarbon dioxideCarbon dioxide laserScarsMedicineLaserSurgeryLaser surgeryChemistryPhysicsOptics

Abstract

fetched live from OpenAlex

Object: The aim of this study was to compare the long-term effects of fractional carbon dioxide (CO 2 ) laser treatment with traditional therapy on surgical scars by analyzing and comparing observational indicators. Approach: A randomized controlled trial was conducted on 116 patients who received scar treatment in our hospital, of which 58 patients received fractional CO 2 laser treatment, and 58 patients received injection treatment. The outcome measures comprised the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS). The observation intervals occur at specific times. Evaluated at 6 months of follow-up, the outcome was blinded, on-site evaluation using the dermatological appearance scale (DAS) and visual analog scale (VAS). Results: Patients in the fractional carbon-dioxide laser (CO 2 FL) group rated better than those in the injection group in the POSAS, VSS, DAS, and VAS scores ( p &lt; 0.05). The therapeutic efficacy and patients’ satisfaction of the research group were superior to those in the control group. Innovation: Scars following surgical procedures can be treated in a variety of methods, but there is no consensus on the best method. CO 2 FL has exhibited safety and is more effective than traditional injection treatments for surgical scars. It is a worthwhile approach to consider in clinical treatment. Conclusions: This study demonstrates that CO 2 FL achieves more significant long-term results in surgical scars, including improved scar appearance, safety, and patient satisfaction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.426

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.321
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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