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Record W4406877226 · doi:10.1016/j.wneu.2025.123722

Giant, Unruptured, Partially Thrombosed Right Middle Cerebral Artery Aneurysm Treated with 2 Bypasses and Excision

2025· article· en· W4406877226 on OpenAlexfundno aff
Sameer Saleem Tebha, Dale Ding, Madeleine P. Strohl, Isaac Josh Abecassis

Bibliographic record

VenueWorld Neurosurgery · 2025
Typearticle
Languageen
FieldMedicine
TopicIntracranial Aneurysms: Treatment and Complications
Canadian institutionsnot available
Funders4Cs Foundation
KeywordsMedicineAneurysmMiddle cerebral arteryCraniotomyClipping (morphology)SurgeryRadiologyIschemiaCardiology

Abstract

fetched live from OpenAlex

Aneurysms of the middle cerebral artery (MCA) account for up to 40% of all unruptured intracranial aneurysms 1 , 2 , 3 and 14%–20% of ruptured ones. 4 , 5 Giant MCA aneurysms are rare, representing 10% of cases, 6 but carry an aggressive natural history, with the Japanese Unruptured Cerebral Aneurysm Study reporting an annual rupture rate of approximately 17%. 7 Additionally, patients with unruptured giant MCA aneurysms can present with neurological symptoms, including headache, focal neurological deficit, seizure, or ischemia infarcts. Here, we report a 58-year-old man with a history of alcohol abuse, hypertension, diabetes, and smoking who presented after a first-time seizure ( Video 1 ). Imaging revealed an unruptured, giant (2.9 cm), partially thrombosed right MCA aneurysm. A microsurgical approach using clipping and bypass was planned due to the complexity of the aneurysm. The patient underwent a right frontotemporal craniotomy with radial artery graft extraction 6 weeks later, followed by 2 bypasses: an M2-to-M2 intracranial bypass and a right external carotid-to-M2 bypass using the radial artery graft. The aneurysm was successfully excised. An otolaryngologist assisted with the radial artery graft extraction during the craniotomy and neck dissection. This case highlights the technical complexities involved in managing giant aneurysms via microsurgical technique, including appropriate preoperative strategy development. Informed consent from next of kin as and institutional review board approval were obtained.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.156
Threshold uncertainty score0.886

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.245
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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