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Record W4406980022 · doi:10.5694/mja2.52593

Improving cardiometabolic risk factors in Aboriginal and Torres Strait Islander people in northeast Arnhem Land: single arm trial of a co‐designed dietary and lifestyle program

2025· article· en· W4406980022 on OpenAlexfundno aff
Hasthi U. Dissanayake, George Guruwiwi, Joanne Garnggulkpuy Dhurrkay, Sabine Braat, Benjamin Harrap, Tim Trudgen, Sarah Hanieh, Bronwyn Clark, Michaela Spencer, Michael Christie, Emma Tonkin, Emily Armstrong, Leonard C. Harrison, John M. Wentworth, Julie Brimblecombe, Beverley‐Ann Biggs

Bibliographic record

VenueThe Medical Journal of Australia · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicIndigenous Health, Education, and Rights
Canadian institutionsnot available
FundersInstitute of Infection and ImmunityNational Health and Medical Research CouncilMedical Research CouncilUniversity of Melbourne
KeywordsWaistOverweightMedicineBody mass indexWeight lossConfidence intervalObesityGerontologyDemographyPhysical therapyInternal medicine

Abstract

fetched live from OpenAlex

Abstract Objective To evaluate the impact of a 4‐month dietary and lifestyle program co‐designed and led by Aboriginal and Torres Strait Islander people on weight and metabolic markers, diet, and physical activity in overweight and obese adults in a remote Indigenous community. Study design Single arm, pre–post intervention study. Setting, participants Adult residents (18–65 years) of a remote Northern Territory community with body mass index (BMI) values of at least 25 kg/m 2 or waist circumferences exceeding 94 cm (men) or 80 cm (women). Intervention Hope for Health, a culturally sensitive 4‐month program supporting self‐managed health improvement based on dietary and lifestyle change, 1 August to 30 November 2022. Main outcome measures Weight loss of at least 5%; changes in BMI, waist circumference, other metabolic markers (blood pressure, biomarkers of metabolic health and inflammation), diet, and physical activity; participant perceptions of the program. Results We assessed outcomes for 55 participants who completed weight assessments at both baseline and program end (mean age, 42.5 years [standard deviation, 10.1 years]; 36 women [65%]). Forty participants lost and 15 gained weight; overall mean weight loss was 1.5 kg (95% confidence interval [CI], 0.5–2.4 kg), and ten participants (18%; 95% CI, 9–31%) achieved at least 5% weight reduction. The mean change in BMI (53 participants) was –0.60 kg/m 2 (95% CI, –0.93 to –0.27 kg/m 2 ), in waist circumference (53 participants) –3.2 cm (95% CI, –4.7 to –1.7 cm), and in low‐density lipoprotein cholesterol level (37 participants) –0.28 mmol/L (95% CI, –0.47 to –0.08 mmol/L); the relative decline in the HbA 1c level geometric mean (50 participants) was 11% (95% CI, 6–15%). The intake of breads and cereals (median change, –1.5 [95% CI, –2.0 to –1.0] serves/day) and sugar‐sweetened beverages (–0.6 [95% CI, –1.4 to –0.1] serves/day) declined; the amount of moderate and vigorous physical activity increased by a median of 103 min/day (95% CI, 74–136 min/day; 19 participants). The program focus on integrating healthy bodies and networks of kin, healthy governance, vibrant language and ceremony, and a healthy environment were seen as central to its value and benefit. Conclusions Community appreciation of the program and the improvements in cardiometabolic risk factors are encouraging, providing an example of a culturally sensitive, co‐designed initiative led by Indigenous people for reducing the prevalence of chronic disease in remote areas. Trial registration Australian New Zealand Clinical Trials Registry (ACTRN12622000174785; prospective: 2 February 2022).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.306
Threshold uncertainty score0.846

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.354
Teacher spread0.334 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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