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Record W4407052414 · doi:10.1002/vrc2.1105

Treatment of focal junctional tachycardia using ivabradine in a dog

2025· article· en· W4407052414 on OpenAlex
Joao Escalda, Catheryn Partington, José Novo Matos

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueVeterinary Record Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrhythmias and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineIvabradineHeart failureCardiologyTachycardiaInternal medicineSpironolactoneHeart rateFurosemideBlood pressure

Abstract

fetched live from OpenAlex

Abstract A 10‐year‐old labrador retriever was referred as an emergency due to ascites and lethargy. Physical examination revealed a regular tachycardia at 160 beats per minute with a Grade 3/6, left apical systolic heart murmur. The dog was diagnosed with severe myxomatous mitral valve disease with biventricular congestive heart failure (mild pulmonary oedema and severe ascites) and focal junctional tachycardia. Congestive heart failure was managed with pimobendan, furosemide and benazepril/spironolactone. Ivabradine, a funny channel blocker, was used for rate control of the focal junctional tachycardia, and the dog achieved adequate rate control with monotherapy. The dog was euthanased 10 months after the initial presentation due to refractory congestive heart failure. This case report suggests that ivabradine might be useful for rate control in focal junctional tachycardia, but further studies are required to confirm this observation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.124
Threshold uncertainty score0.634

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.347
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it