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Record W4407223165 · doi:10.1037/abn0000969

Delineating empirically plausible causal pathways to suicidality among people at clinical high risk for psychosis.

2025· article· en· W4407223165 on OpenAlex
Michael V. Bronstein, Erich Kummerfeld, Carrie E. Bearden, Barbara A. Cornblatt, Elaine F. Walker, Scott W. Woods, Daniel H. Mathalon, Diana O. Perkins, Kristen S. Cadenhead, Jean Addington, Tyrone D. Cannon, Sophia Vinogradov

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Psychopathology and Clinical Science · 2025
Typearticle
Languageen
FieldPsychology
TopicSuicide and Self-Harm Studies
Canadian institutionsUniversity of Calgary
FundersNational Institute of Mental HealthCommonwealth of Massachusetts
KeywordsPsychosisPsychologyClinical psychologyPsychiatry

Abstract

fetched live from OpenAlex

= 266). Data on correlates of suicidality-including depression and attenuated psychosis symptoms, sleep, and childhood trauma-from two initial study timepoints were submitted to the greedy relaxations of the sparsest permutation algorithm. Intervention calculus was used to estimate the (lower bound) total empirically plausible causal effects of each variable on suicidality. Across both samples, greedy relaxations of the sparsest permutation suggested that symptoms of depression-particularly hopelessness, self-deprecation, and depressed mood-were likely direct causes of suicidality among people at CHR for psychosis. Across samples and measurement time points, intervention calculus indicated that depressed mood exerted the greatest influence over suicidality of all measured variables. This study provides data-driven, testable hypotheses about the causal pathways leading to suicidality among people at CHR for psychosis and suggests promising targets for interventions on suicidality tailored to these individuals. Future experimental research should test these hypotheses by, for example, comparing the suicide risk reduction afforded by interventions aimed at each aforementioned target. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.853

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0160.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.075
GPT teacher head0.457
Teacher spread0.382 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it