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Record W4407260126 · doi:10.1177/09731296241312483

Effects of <i>Asiaticosides</i> on Scar Recovery and Psychological Well-being in Patients with Scald Injuries

2025· article· en· W4407260126 on OpenAlexaboutno aff
Li Li, Le Liu

Bibliographic record

VenuePharmacognosy Magazine · 2025
Typearticle
Languageen
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVisual analogue scalePsychological interventionContext (archaeology)CentellaScarsAnxietyDepression (economics)Physical therapyNursingSurgeryPsychiatryTraditional medicine

Abstract

fetched live from OpenAlex

Background Scar recovery in elderly burn patients is essential for wound healing and psychological well-being. Total glycosides from Centella asiatica have gained attention for their anti-inflammatory, antioxidant, and wound-healing properties, showing promise in burn care. Objectives This study investigates the synergistic effects of combined nursing interventions and Asiaticosides on scar recovery and psychological well-being in patients undergoing scald scar repair. The pharmacological properties of these glycosides, including their anti-inflammatory, anti-oxidant, and wound-healing potential, are explored in the context of clinical care to enhance patient outcomes. Materials and Methods A cohort of 184 patients treated for scald scars between April 2023 and April 2024 was divided into two groups: an observation group receiving combined nursing interventions with Asiaticosides , and a comparison group receiving standard care. Scar assessment was conducted using the Vancouver Scar Scale (VSS), pain was measured by the Visual Analogue Scale (VAS), and psychological states were evaluated using the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Results Statistically significant improvements were observed in the observation group, including reduced VSS and VAS scores, as well as enhanced psychological states, compared to the control group ( p < 0.05). The glycosides facilitated faster scar healing, reduced inflammation, and improved overall patient well-being. Conclusion Asiaticosides exhibit promising therapeutic potential in enhancing scar recovery and psychological health in elderly scald patients when combined with comprehensive nursing care. Further research into their mechanisms may solidify their role in integrated scald injury management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.296
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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