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Record W4407265729 · doi:10.1093/aje/kwaf018

Employment quality and suicide, drug poisoning, and alcohol-attributable mortality

2025· article· en· W4407265729 on OpenAlexafffundabout
Alessandra T. Andreacchi, Anne Fuller, Peter Smith, Alexandra Blair, Nancy Carnide, Roman Pabayo, Brendan T. Smith, Arjumand Siddiqi, Faraz Vahid Shahidi

Bibliographic record

VenueAmerican Journal of Epidemiology · 2025
Typearticle
Languageen
FieldHealth Professions
TopicEmployment and Welfare Studies
Canadian institutionsUniversity of AlbertaPublic Health Agency of CanadaHospital for Sick ChildrenPublic Health OntarioMcMaster University Medical CentreInstitute for Work & HealthMcMaster UniversityToronto Metropolitan UniversityUniversity of Toronto
FundersDepartment of Epidemiology, Biostatistics and Occupational Health, McGill UniversityMcGill University
KeywordsMedicinePoisson regressionDemographyMortality rateEnvironmental healthCohortPoison controlPopulationSurgeryInternal medicine

Abstract

fetched live from OpenAlex

Suicide, drug poisoning, and alcohol-attributable mortality (SDAM)-often labeled "deaths of despair"-are increasing among working-aged individuals in many high-income countries. We examined the association between employment quality and SDAM in Canada. Census records from the 2006 Canadian Census Health and Environment Cohort (n = 2 805 550) were linked to mortality data from 2006 to 2019. Latent class analysis identified 5 employment quality types: standard (secure and rewarding), portfolio (rewarding but demanding), marginal (limited hours and earnings), intermittent (sporadic and unstable), and precarious (insecure and unrewarding). Poisson regression models estimated sex/gender-stratified associations between employment quality type and SDAM separately. We observed a consistent mortality gradient across employment quality groups, with lower-quality employment-and precarious employment in particular-associated with increased rates of SDAM relative to higher-quality (ie, standard) employment. For example, precarious employment was associated with a more than 3-fold rate of drug poisoning deaths among women (rate ratio [RR] = 3.58; 95% CI, 3.21-4.00) and a more than 2-fold rate of alcohol-attributable death among men (RR = 2.22; 95% CI, 2.07-2.38). Employment quality is an important determinant of SDAM, with varying associations by sex/gender. Improvements in employment conditions may help reduce the burden of premature deaths attributable to suicide and substance use.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.836
Threshold uncertainty score0.330

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.168
GPT teacher head0.522
Teacher spread0.355 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes3
Has abstractyes

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