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Record W4407277229 · doi:10.1016/j.ebiom.2025.105592

The ongoing importance of patient-informed, collaborative research in advancing the definition and harmonization of post COVID-19 condition (PCC) subtypes across diverse populations

2025· article· en· W4407277229 on OpenAlexaff
Erin Collins, Nicole Shaver, Julian Little

Bibliographic record

VenueEBioMedicine · 2025
Typearticle
Languageen
FieldMedicine
TopicLong-Term Effects of COVID-19
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsCoronavirus disease 2019 (COVID-19)Harmonization2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus InfectionsBetacoronavirusMEDLINEPandemicMedicineBiologyVirologyPathologyOutbreakInfectious disease (medical specialty)Disease

Abstract

fetched live from OpenAlex

Post-COVID-19 Condition (PCC), also referred to as long COVID, post-acute sequelae, or post-acute COVID-19 syndrome, remains a major challenge to individual well-being, healthcare systems, and national economies. During the earlier phases of the pandemic, a broad and generalized definition of PCC was widely adopted. As research progressed through subsequent waves and into the post-pandemic period, efforts shifted toward identifying distinct symptom clusters, or subtypes.1 This approach acknowledges that PCC likely encompasses multiple subsyndromes, each potentially driven by unique underlying etiologies, highlighting the need for more targeted and nuanced understanding and interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.915

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.409
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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