Comparative analysis of piroxicam and post-isometric exercises in knee osteoarthritis in school teachers
Bibliographic record
Abstract
BackgroundSchool teachers often have knee osteoarthritis due to the nature of their work.ObjectiveTo compare the effects of post-isometric exercise and piroxicam on pain and functional impairment in school teachers having knee osteoarthritis.MethodA pragmatic, community-based, double-blinded, randomized clinical trial (IRCT20230202057310N4) was conducted was conducted at Muhammad Physical Therapy Clinic and Rehabilitation Center, Multan, Pakistan from September 2023 to July after approval from the Institutional Ethical Committee (). A total of 70 pre-diagnosed osteoarthritis patients were randomly assigned to two groups after enrollment using the lottery method. Patients of Group A were treated with post-isometric exercises for 12 weeks (3 sessions per week and each session lasted for 45 min), while those in Group B were given piroxicam (given orally 20 mg twice a day for 12 weeks). At baseline and the 18th session, pain and daily activities were measured using the Pain Catastrophizing Scale (PCS), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale, and Numerical Pain Rating Scale (NPRS), biochemical (ESR, CRP, and WBCs) and radiological (X-rays) parameters were evaluated. The data was analyzed by using SPSS-23. The independent t-test compared differences between two unrelated groups while the paired t-test assessed differences within the same group. P-value <0.005 was considered significant.ResultsOut of 70 patients, 68 patients were assessed and there were 46 females and 21 males. The results showed a highly significant improvement in flexion (p = 0.001), WOMAC ADLs (p = 0.001), WOMAC stiffness (p = 0.004), PCS (p = 0.001) in group-A than group-B. Similarly, there was a highly significant improvement in NPRS (p = 0.001), WOMAC pain (p = 0.001), WBCs % (p = 0.002), ESR (p = 0.002) and CRP (p = 0.003) in group-B than group-A, underscoring the effectiveness of the post-isometric exercises.ConclusionThese findings suggest that post-isometric exercises could be a more beneficial treatment option than piroxicam for knee osteoarthritis. The practical implications of this research are significant, as it demonstrates that post-isometric exercises not only enhance functional results but also reduce pain severity, offering a promising alternative to traditional medication.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.002 | 0.005 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".