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A scoping review of harm reduction practices and possibilities among indigenous populations in Australia, Canada, and the United States

2025· review· en· W4407397660 on OpenAlexafffundabout
Camille Zolopa, Seema L. Clifasefi, Sophia Dobischok, Natalia Gala, Hannah Fraser-Purdy, Morgan Kahentonni Phillips, Sophie Blackmore, Dennis C. Wendt

Bibliographic record

VenueDrug and Alcohol Dependence · 2025
Typereview
Languageen
FieldMedicine
TopicHIV, Drug Use, Sexual Risk
Canadian institutionsConcordia UniversityHôpital Notre-DameMcGill University
FundersInstitute of Space and Astronautical ScienceNational Institute on Alcohol Abuse and AlcoholismFonds de Recherche du Québec - SantéNational Institutes of HealthNational Institute on Drug AbuseMcGill University
KeywordsIndigenousHarm reductionHarmEnvironmental healthPolitical scienceCriminologyGeographyMedicinePsychologyPublic healthLawNursingEcologyBiology

Abstract

fetched live from OpenAlex

BACKGROUND: There is a great diversity of traditions, practices, and experiences among the Indigenous Peoples of North America and Oceania. However, Indigenous Peoples across these regions are affected by the historical and ongoing violence of settler colonialism, resulting in disproportionately heightened drug-related harms. 'Harm reduction' refers to both an ethos and a set of strategies intended to lessen negative social and/or health effects associated with drug use. While harm reduction could therefore be valuable to Indigenous people who use drugs, important concerns remain regarding the culturally specific implementation and outcomes of such strategies. A clearer picture of research regarding harm reduction in Indigenous communities is needed. METHOD: We conducted a scoping review of primary studies regarding drug use harm reduction approaches among Indigenous communities in Australia, Canada, New Zealand, and the United States. We included studies that (1) reported on harm reduction principles or strategies; and (2) either reported disaggregated results for Indigenous participants or were based on a sample in which at least half of the participants identified as Indigenous. Medline and PsycINFO were searched in March 2024; screening by two independent reviewers was completed in April 2024. FINDINGS: Screening 578 references generated a corpus of 28 studies, 16 (57 %) of which were conducted in Canada. Indigenous people who use drugs generally reported favourable attitudes towards harm reduction initiatives; other community members and healthcare providers were more hesitant. A variety of harm reduction strategies were discussed, most commonly needle-syringe programs (n = 8, 29 %). Barriers included the availability and acceptability of harm reduction services. Community members expressed concerns regarding cultural appropriateness, but also offered possibilities for improved integration of harm reduction into Indigenous traditions and practices. INTERPRETATION: This review indicated an emerging, wide-ranging, and somewhat disparate body of literature. While barriers remain, there are promising possibilities for reconceptualizing harm reduction from an Indigenous ethos.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.325
Threshold uncertainty score0.775

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.149
GPT teacher head0.447
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes3
Has abstractyes

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