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Record W4407538032 · doi:10.1038/s41467-025-56776-z

Characterising the asynchronous resurgence of common respiratory viruses following the COVID-19 pandemic

2025· review· en· W4407538032 on OpenAlexaff
Chenkai Zhao, Tiantian Zhang, Ling Guo, Shiqi Sun, Yumeng Miao, Chee Fu Yung, Jane Tomlinson, K. A. Stolyarov, Zakhar Shchomak, Yong Poovorawan, D. James Nokes, Carmen Muñoz‐Almagro, Michal Mandelboim, James W. Keck, Joanne M. Langley, Terho Heikkinen, Jikui Deng, Philippe Colson, Giorgi Chakhunashvili, Mauricio T. Caballero, Louis Bont, Daniel R. Feikin, Harish Nair, Xin Wang, You Li, Yara‐Natalie Abo, Andrew J. Daley, Gregory Waller, Daria Danilenko, Andrey B. Komissarov, Teresa Bandeira, Nongruthai Suntronwong, Siripat Pasittungkul, Esther Nyadzua Katama, Cristian Launes, Quique Bassat, Ital Nemet, Jennifer Dobson, Jiajia Bi, Guangcheng Deng, Céline Boschi, Bernard La Scola, Didier Raoult, Irakli Karseladze, Khatuna Zakhashvili, Olgha Tarkhan‐Mouravi, Julia Dvorkin, Marie Billard

Bibliographic record

VenueNature Communications · 2025
Typereview
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsCentre for Global Health ResearchNova Scotia Health AuthorityDalhousie University
FundersNational Natural Science Foundation of ChinaWorld Health Organization
KeywordsHuman metapneumovirusRhinovirusVirologyPandemicVirusMetapneumovirusBiologyAsynchrony (computer programming)CoronavirusInfluenza A virusRespiratory systemCoronavirus disease 2019 (COVID-19)Respiratory tract infectionsMedicineAsynchronous communication

Abstract

fetched live from OpenAlex

The COVID-19 pandemic and relevant non-pharmaceutical interventions (NPIs) interrupted the circulation of common respiratory viruses. These viruses demonstrated an unprecedented asynchronous resurgence as NPIs were relaxed. We compiled a global dataset from a systematic review, online surveillance reports and unpublished data from Respiratory Virus Global Epidemiology Network, encompassing 92 sites. We compared the resurgence timings of respiratory viruses within each site and synthesised differences in timings across sites, using a generalised linear mixed-effects model. We revealed a distinct sequential timing in the first post-pandemic resurgence: rhinovirus resurged the earliest, followed by seasonal coronavirus, parainfluenza virus, respiratory syncytial virus, adenovirus, metapneumovirus and influenza A virus, with influenza B virus exhibiting the latest resurgence. Similar sequential timing was observed in the second resurgence except influenza A virus caught up with metapneumovirus. The consistent asynchrony across geographical regions suggests that virus-specific characteristics, rather than location-specific factors, determining the relative timing of resurgence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.019
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0050.005
Science and technology studies0.0000.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.269
GPT teacher head0.528
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations66
Published2025
Admission routes1
Has abstractyes

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Same venueNature CommunicationsSame topicRespiratory viral infections researchFrench-language works237,207