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Record W4407638182 · doi:10.1109/jbhi.2025.3542394

Decouple-and-Couple Learning in Multi-Modal Brain Tumor Segmentation

2025· article· en· W4407638182 on OpenAlexaff
Fuan Xiao, Chaojie Ji, Zheng Zhang, Ruxin Wang

Bibliographic record

VenueIEEE Journal of Biomedical and Health Informatics · 2025
Typearticle
Languageen
FieldNeuroscience
TopicBrain Tumor Detection and Classification
Canadian institutionsUniversity of British Columbia
FundersNational Key Research and Development Program of ChinaNational Natural Science Foundation of China
KeywordsComputer scienceModalArtificial intelligenceSegmentationComputer visionPattern recognition (psychology)Materials science

Abstract

fetched live from OpenAlex

Exploiting multi-modal magnetic resonance imaging complementary information for brain tumor segmentation is still a challenging task. Existing methods are usually inclined to learn the joint representation of all tumor regions indiscriminately, thus salient sub-region or healthy tissue would be dominant during the training procedure, which leads to a biased and limited representation performance. In this study, a novel transformer-based multi-modal brain tumor segmentation approach is developed by decoupling and coupling strategy. First, Anatomy-induced Region Decoupler decouples the representation of the tumor scattered in different semantic sub-regions following anatomical view, which forces the model to fully learn intra-region representation separately with multiple modalities context. Additionally, we introduce the collaborative decoupling of the corresponding sub-region edge to serve auxiliary cues. We then design the Edge-supported Intra-region Coupler to separately couple edge and object learning within each anatomical sub-region structure. Lastly, the Mutual Cross-region Coupler is further applied to implement mutual improvement by coupling complementary gains among the above decoupled sub-regions. Extensive experiments clearly demonstrate that our method outperforms current state-of-the-arts for brain tumor segmentation on BRATS2018, BRATS2020, MSD, and BRATS2021 benchmarks while retaining high efficiency in the learning procedure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.901
Threshold uncertainty score0.233

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.361
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2025
Admission routes1
Has abstractyes

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