MétaCan
Menu
Back to cohort
Record W4407727560 · doi:10.1016/j.heliyon.2025.e42815

The application of multiple linear regression methods to FTIR spectra of fingernails for predicting gender and age of human subjects

2025· article· en· W4407727560 on OpenAlexaff
Leonard Mihaly Cozmuța

Bibliographic record

VenueHeliyon · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSpectroscopy Techniques in Biomedical and Chemical Research
Canadian institutionsScience North
Fundersnot available
KeywordsLinear regressionFourier transform infrared spectroscopyRegression analysisStatisticsMathematicsEngineeringChemical engineering

Abstract

fetched live from OpenAlex

The paper explores the accuracy of gender and age prediction of human subjects based on the chemometric analysis of FTIR spectra from fingernails. The baseline and scaling over the 0-1 range were applied to FTIR spectra from fingernails of 123 subjects, and wavenumbers for which absorbance values showed a statistically significant correlation with gender and age were identified. The prediction accuracy was analyzed using: Multiple linear regression, Forward stepwise regression, Backward stepwise regression, Principal component regression, and Partial least squares regression. As regard the gender prediction, the principal component regression model proved to be the most accurate, with 8 extracted components allowing a prediction of 93.50 % (86.00 % for women, 98.63 % for men). The predictive power of the model showed that in case of new subjects, gender classification could be done in 91.06 % of cases (84.00 % for women, 95.89 % for men). For age prediction, the optimal backward stepwise regression model with 6 statistically significant predictors showed an average error of 11.39 % (13.70 % for women, 9.81 % for men). The predictive power of the model was 12.13 % (11.73 % for women, 10.35 % for men). The age prediction was less accurate, with a maximum error of 10.00 % achieved only in the case of 65.04 % of subjects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.101
Threshold uncertainty score0.165

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.423
Teacher spread0.396 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueHeliyonSame topicSpectroscopy Techniques in Biomedical and Chemical ResearchFrench-language works237,207