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Record W4407738730 · doi:10.1371/journal.pmen.0000217

Muscle-building supplement use is associated with muscle dysmorphia symptomatology among Canadian adolescents and young adults

2025· article· en· W4407738730 on OpenAlexafffundabout
Kyle T. Ganson, Rachel F. Rodgers, Alexander Testa, Stuart B. Murray, Jason M. Nagata

Bibliographic record

VenuePLOS mental health. · 2025
Typearticle
Languageen
FieldPsychology
TopicEating Disorders and Behaviors
Canadian institutionsUniversity of Toronto
FundersConnaught Fund
KeywordsMedicinePsychologyClinical psychology

Abstract

fetched live from OpenAlex

This study investigated the association between muscle-building supplement use and muscle dysmorphia symptomatology among Canadian adolescents and young adults. Data from the Canadian Study of Adolescent Health Behaviors (N = 2,731) were analyzed. Multiple linear and logistic regression analyses were used to assess the association between six commonly used muscle-building supplements (e.g., amino acids/branched-chain amino acids, creatine monohydrate, pre-workout drinks or powders, protein bars, weight/mass gainers, and whey protein shakes or powders), and an aggregated sum score of muscle-building supplements used, and muscle dysmorphia symptomatology (measured using the Muscle Dysmorphic Disorder Inventory [MDDI]), including scoring above the clinical cut-off (≥ 40 on the MDDI). The mean age of the sample was 22.9 years (SD = 3.9), 54.3% identified as a cisgender girl or woman, 62.4% identified as white, and 58.8% identified as heterosexual. Findings revealed that use of all six muscle-building supplements, and using a greater number of muscle-building supplements, were associated with greater total muscle dysmorphia symptomatology, as well as greater odds of meeting the clinical cut-off for muscle dysmorphia. These findings add to a growing body of literature on the association between muscle-building supplement use and muscle dysmorphia symptomatology by including multiple muscle-building supplements and utilizing a diverse, national sample of adolescents and young adults. Findings warrant further investigation and the development of intervention strategies to decrease the use of increasingly normalized muscle-building supplements and muscle dysmorphia symptomatology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.161
Threshold uncertainty score0.965

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.287
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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