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Using Invitation Letters to Increase HPV Vaccination Among Adult Women

2025· preprint· en· W4407777150 on OpenAlexfundaboutno aff
Kelly Bunzeluk, Laura Coulter, Donna Turner, Carla Krueger, Austin Hill

Bibliographic record

VenuePreprints.org · 2025
Typepreprint
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsnot available
FundersCancerCare Manitoba Foundation
KeywordsVaccinationMedicineDemographyVirologySociology

Abstract

fetched live from OpenAlex

(1) Background: In Manitoba, most people get the HPV vaccine in the publicly-funded school-based program. If they miss the school-based program, they remain eligible for the free HPV immunization program. This study explored whether invitation and reminder letters would increase HPV vaccine uptake among adult women who remained eligible for the publicly-funded program. (2) Methods: Eligible individuals were randomized into three groups of 4,650 women. Intervention groups I and II were mailed an information package inviting them to be vaccinated. Six weeks later, intervention group II received a reminder letter if they remained unvaccinated. Vaccination status, defined as at least one dose of an approved HPV vaccine, was calculated six months after the packages were mailed. (3) Results: 4.0% of individuals in intervention group II (invitation/reminder) and 2.5% of individuals in intervention group I (invitation) received one dose of the HPV vaccine. Compared to the control group, sending invitation/reminder and invitation packages increased the likelihood of getting at least one dose of the HPV vaccine by 4.9 times (3.4 - 6.9) and 3.0 (2.1 - 4.4) times, respectively. (4) Conclusion: Sending invitation and reminder letters to unvaccinated women may be an effective and low-cost way to increase HPV vaccination coverage among adults who are eligible for the publicly-funded immunization program.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.380
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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