MétaCan
Menu
Back to cohort
Record W4407781655 · doi:10.1016/j.canep.2025.102774

Age-specific lung cancer incidence trends in Canada from 1992 to 2022

2025· article· en· W4407781655 on OpenAlexafffundabout
Matthew T. Warkentin, Yibing Ruan, K.J. Graff, Alain Tremblay, Darren R. Brenner

Bibliographic record

VenueCancer Epidemiology · 2025
Typearticle
Languageen
FieldMedicine
TopicLung Cancer Treatments and Mutations
Canadian institutionsAlberta Health ServicesAlberta Cancer FoundationUniversity of Calgary
FundersCanadian Cancer Society
KeywordsMedicineIncidence (geometry)Lung cancerCancerDemographyOncologyInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Lung cancer incidence has historically been higher in males than females, but these rates have been converging. Here we detail the trends in age-specific lung cancer incidence in Canada from 1992 to 2022. METHODS: Lung cancer incidence data from 1992 to 2022 by sex and age were obtained from Statistics Canada. We report lung cancer incidence rates and annual percent changes (APC) based on Joinpoint Regression. Birth cohort effects are presented as incidence rate ratios (IRR) with 95 % confidence intervals (CI). RESULTS: Lung cancer incidence has decreased among males aged 35 or above with the largest decreases occurring among those 65 or above. Females under 55 showed similar decreasing trends. However, females 55 or above show stable or increasing incidence rates until around 2017 when rates began decreasing significantly. Birth cohort analysis showed males born after 1957 have lower risk compared to those born at of before 1957. Females risk peaked in 1943-47 and the risk after 1957 slowly returned to early twentieth century levels. CONCLUSION: The sex difference in lung cancer incidence continues to narrow. Lung cancer rates among males have declined for decades, while the decline among females is more recent and incidence is higher for females at younger ages for the first time.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.231
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.412
Teacher spread0.373 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

Explore more

Same venueCancer EpidemiologySame topicLung Cancer Treatments and MutationsFrench-language works237,207