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Record W4407797424 · doi:10.29169/1927-5951.2025.15.01

Beyond the Spice Rack: The Therapeutic Benefits of Curcumin for Male Reproductive Health

2025· article· en· W4407797424 on OpenAlex
Timothy Adeolu Amusan, Mathias Abiodun Emokpae

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCurcumin's Biomedical Applications
Canadian institutionsnot available
Fundersnot available
KeywordsCurcuminSpiceRackPharmacologyMedicineEngineeringElectrical engineering

Abstract

fetched live from OpenAlex

Turmeric, derived from the rhizome of Curcuma longa, is a widely utilized spice. It is characterized by a warm and slightly bitter flavor, and is often employed to enhance the taste and color of curry powders. The active compound, curcumin has been the subject of extensive research due to its anti-inflammatory, antioxidant, and potential anticancer properties, among others. This review explores the therapeutic potential of curcumin, the active ingredient in turmeric, for male reproductive health, going beyond its culinary uses. The articles used for this narrative review were obtained from some search engines including National Library of Medicine (PubMed), Science Alert, Google Scholar, Excerta Medical database (EMBASE) and Cumulated Index to Nursing and Allied Health Literature (CINAHL). It summarizes the current scientific evidence regarding curcumin's effects on various aspects of male fertility, including sperm quality. It also highlights curcumin's antioxidant, anti-inflammatory, anti-apoptotic properties and how these contribute to its potential benefits in addressing male reproductive issues. Evidence from the overview of existing literature suggests the potential benefits of curcumin supplementation in alleviating male infertility. An avenue for future investigations into curcumin's role in maintaining and improving male reproductive health in human is widely open.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.433
Threshold uncertainty score0.195

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.386
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it