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Record W4407848241 · doi:10.1186/s12882-024-03908-0

Correlation between intradialytic blood pressure variability and cognitive impairment in patients on maintenance hemodialysis

2025· article· en· W4407848241 on OpenAlexaboutno aff
Jingfang Wan, Jing Pan, Lili Fu, Dandan He, Yi Yao, Yani He, Kehong Chen

Bibliographic record

VenueBMC Nephrology · 2025
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsnot available
FundersCentre Scientifique et Technique du BâtimentNational Natural Science Foundation of China
KeywordsMedicineNephrologyHemodialysisInternal medicineBlood pressureCardiologyCorrelationCognitive impairmentIntensive care medicineDisease

Abstract

fetched live from OpenAlex

BACKGROUND: The relationship between intradialytic blood pressure variability (BPV) and mild cognitive impairment (MCI) in maintenance hemodialysis (MHD) patients is currently unclear. Our present study aimed to illustrate the correlation between intra-dialysis BPV and CI in MHD patients. METHODS: Intradialytic SBP within 3 months before cognitive assessment of the patients were collected as baseline data and averaged as final data. The intradialytic SBP was converted to the following 4 candidate short-term BPV indices: standard deviation (SD), coefficient of variation (CV), average real variability (ARV), RANGE. Overall cognitive function was assessed by the Montreal Cognitive Assessment (MoCA) scale. RESULTS: The study finally enrolled 170 patients with 6662 dialysis records and 26,580 SBP measurements. The mean age of the patients was 57.99 years, the MCI prevalence was 78.24%. Intradialytic SBP ARV (average real variability) was notably higher in patients with MCI than in the non-MCI (NMCI) group (8.91 vs. 7.60, P = 0.042), but there was no statistical difference in the mean SBP and other BPV indices between the two groups. There was a non-linear relationship between SBP ARV and MCI, and the inflection point of SBP ARV was 7.52. CONCLUSION: Our study found that high SBP ARV was closely associated with MCI, indicating that high SBP ARV may act as an indicator of MCI in MHD patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.239
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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