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Record W4407852126 · doi:10.1016/j.ocarto.2025.100588

Optimizing osteoarthritis care through clinical and community partnership: Results of an exploratory trial

2025· article· en· W4407852126 on OpenAlexaboutno aff
Kelli D. Allen, Liubov Arbeeva, Leigh F. Callahan, Katherine Combs, Yvonne M. Golightly, Derek Hales, Carla Hill, Katie F. Huffman, Amanda E. Nelson, Jennifer Rees, Todd A. Schwartz

Bibliographic record

VenueOsteoarthritis and Cartilage Open · 2025
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
FundersNational Institute of Arthritis and Musculoskeletal and Skin DiseasesHealth Services Research and DevelopmentU.S. Department of Veterans Affairs
KeywordsMedicinePhysical therapyWOMACRandomized controlled trialConfidence intervalWeight lossOsteoarthritisOverweightAttendanceReferralObesityFamily medicineInternal medicineAlternative medicine

Abstract

fetched live from OpenAlex

Background/Purpose: To conduct an exploratory trial of a clinic-community care model (OA CARE) for managing osteoarthritis (OA). Design: Participants (n ​= ​60) with symptomatic knee or hip OA and overweight/obesity were randomized to OA CARE or a usual care control group (UC). Participants in the OA CARE group received a 12-month medical membership to a local YMCA, which included a 12-week weight loss program and access to exercise programming, as well as referrals to rehabilitation, nutrition, sleep-related and psychological services. Participants' primary care clinicians were given a video-based summary of OA treatment guidelines. Feasibility metrics included engagement with the weight loss program and exercise resources. Outcomes were assessed at baseline, 6-months and 12-months. The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Outcomes were analyzed between groups across time points using general linear mixed models. Results: Eighty-seven percent of the OA CARE group participated in the weight loss program, with a mean attendance of 9.2 sessions; 57 ​% participated in an exercise class. At 6-months, there was a statistically significant between-group difference in change in WOMAC total scores, with the OA CARE group showing greater improvement (-11.0, 95 ​% Confidence Interval -20.1, -1.9). At 12-months, the between-group change in WOMAC score was not statistically significant, though there was a small difference in favor of OA CARE Group (-4.9, 95 ​% Confidence Interval -14.1, 4.3). Conclusion: Feasibility metrics were positive, but effects of OA CARE were modest, and a more intensive approach may be needed to enhance impacts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.875
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.352
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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