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Record W4407933016 · doi:10.1249/mss.0000000000003684

A Protocol to Establish Exercise Intensity Domains for Aerobic Exercise Training in Coronary Artery Disease

2025· article· en· W4407933016 on OpenAlexaff
Robin Faricier, Randi R. Keltz, Tim Hartley, Juan M. Murias, A. Huitema, Robert S. McKelvie, Neville Suskin, Daniel A. Keir

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsToronto General HospitalSt Joseph's Health CareLawson Health Research InstituteWestern University
Fundersnot available
KeywordsAerobic exerciseCoronary artery diseaseMedicineCardiologyIntensity (physics)Physical therapyExercise intensityTraining (meteorology)Internal medicineProtocol (science)Physical medicine and rehabilitationHeart rateBlood pressurePhysicsPathologyAlternative medicine

Abstract

fetched live from OpenAlex

INTRODUCTION/PURPOSE: The oxygen uptake (V̇O 2 )-power output (PO) relationship from incremental exercise needs to be adjusted to accurately prescribe constant-intensity exercise training. We assessed the accuracy of a "step-ramp-step" (SRS) protocol for prescribing constant PO exercise within moderate-intensity (below estimated lactate threshold, θ LT ), heavy-intensity (between θ LT and respiratory compensation point, RCP), and severe-intensity (above RCP) domains in 14 patients with coronary artery disease (CAD). METHODS: The SRS protocol included the following: 6 min of cycling at 25-40 W, a ramp-incremental test until task failure (5-15 W · min -1 ), and, after a 20 min recovery, 12 min of cycling at ~50%-60% of peak ramp PO. On separate days, patients performed three domain-specific constant PO exercises at 80% θ LT (moderate intensity [MOD]), 70% of the difference between θ LT and RCP (heavy intensity [HVY]), and 115% RCP (severe intensity [SEV]). Measured V̇O 2 values for MOD and HVY were compared with those predicted using either SRS-corrected or uncorrected approaches and, for SEV, were compared with peak ramp V̇O 2 . RESULTS: The PO values for MOD, HVY, and SEV were 53 ± 27, 96 ± 50, and 116 ± 56 W, respectively, eliciting V̇O 2 of 1012 ± 362, 1541 ± 638, and 1944 ± 744 mL·min -1 . The SRS-corrected predictions did not differ from measured V̇O 2 for MOD (-25 ± 61 mL·min -1 ; P = 0.201) or HVY (-40 ± 89 mL·min -1 ; P = 0.208), whereas uncorrected predictions underestimated V̇O 2 by -128 ± 72 mL·min -1 ( P = 0.002) and -199 ± 99 mL·min -1 ( P = 0.001) in MOD and HVY, respectively. Peak V̇O 2 from SEV did not differ from the ramp (1906 ± 766 mL·min -1 ; P = 0.759). CONCLUSIONS: In CAD, the V̇O 2 -PO relationship from incremental exercise must be corrected to prescribe constant-intensity training. The SRS protocol is an accurate approach to ensure prescriptive accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.013
Threshold uncertainty score0.043

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0130.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.310
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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