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Record W4407934413 · doi:10.1016/j.brs.2024.12.1012

Accelerated Deep Transcranial Magnetic Stimulation for Stimulant Use Disorder

2025· article· en· W4407934413 on OpenAlexaff
Emma Bousseau, Maxime Richard, Véronique Desbeaumes Jodoin, Daniel M. Blumberger, Travis E. Baker, Elie Bou Assi, Simon Dubreuq, Paul Robert Juster, Didier Jutras Aswad, Paul Lespérance, Jean‐Philippe Miron

Bibliographic record

VenueBrain stimulation · 2025
Typearticle
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsCentre for Addiction and Mental HealthCentre Hospitalier de l’Université de MontréalUniversité du Québec en OutaouaisUniversité de Montréal
Fundersnot available
KeywordsTranscranial magnetic stimulationStimulantDeep transcranial magnetic stimulationStimulationNeurosciencePsychologyMedicinePsychiatry

Abstract

fetched live from OpenAlex

Transcranial direct current stimulation (tDCS), when targeted at the left dorsolateral prefrontal cortex (DLPFC) has been shown to be an effective treatment for depression.However, the underlying mechanism of this effect remains largely unknown.Given that depression can significantly impact how patients process reward-and error-related information, our study aimed to investigate whether tDCS, applied to a non-depressed sample, would modulate the amplitudes of event-related potentials (ERPs) during two cognitive tasks: the gambling doors task and the Go/No-Go task.These tasks provide information on how the participant reacts to reward-and error-related information.In gambling doors task, stimulation had discernible effects on the N1-P2 complex, but it did not significantly influence the reward positivity (RewP) response.Interestingly, the late positive polarity (LPP) showed a modest elevation in the stimulation group.In Go/No-Go task, participants in the stimulation group exhibited shortened reaction times compared to the control group.However, there was no significant difference in the number of errors committed between the two groups.Notably, the amplitude of error-related negativity (ERN) remained consistent across both groups, while the later-emerging error positivity (Pe) was more pronounced in the stimulation group.The results indicate that anodal tDCS targeted at the left DLPFC might alter conscious processing, rather than automatic processing, of error-and reward-related information.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.321
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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